1 to 10 of 25 Results
May 15, 2024 - C03: Modelling of material injection processes into porous structures applied to vertebroplasty
Trivedi, Zubin; Wychowaniec, Jacek K.; Gehweiler, Dominic; Sprecher, Christoph Martin; Boger, Andreas; Gueorguiev, Boyko; D'Este, Matteo; Ricken, Tim; Röhrle, Oliver, 2024, "Data for: Rheological Analysis and Evaluation of Measurement Techniques for the Curing Polymethylmethacrylate Bone Cement in Vertebroplasty", https://doi.org/10.18419/darus-4004, DaRUS, V1, UNF:6:qWipgRgsaAlTQZDkmPv0LQ== [fileUNF]
This dataset includes the measurement data described in the paper "Rheological Analysis and Evaluation of Measurement Techniques for the Curing Polymethylmethacrylate Bone Cement in Vertebroplasty" and additional supplementary data. All data in .csv files except 'Inj1 -- 5' are g... |
Mar 28, 2024 - MD Simulations
Jeltsch, Albert; Schnee, Philipp; Pleiss, Jürgen; Weirich, Sara, 2024, "Additional data related to Weirich et al.: Discovery of new NSD2 non-histone substrates and design of a super-substrate", https://doi.org/10.18419/darus-3815, DaRUS, V1
This data collection contains additional data related to Weirich et al.: "Discovery of new NSD2 non-histone substrates and design of a super-substrate". This includes Modelled structures of NSD2 bound to different peptides Source data of the results of the MD analysis MD simulati... |
Mar 19, 2024 - Institute for Stochastics and Applications
Höpfl, Sebastian, 2024, "Percentile Intervals in Bayesian Inference are Overconfident", https://doi.org/10.18419/darus-4068, DaRUS, V1
This dataset demonstrates the difference in calculating percentile Intervals as approximation for Highest Density Intervals (HDI) vs. Highest Posterior Density (HPD). This is demonstrated with extended partial liver resection data (ZeLeR-study, ethical vote: 2018-1246-Material).... |
Jeltsch, Albert; Bashtrykov, Pavel; Dossmann, Leonie; Emperle, Max, 2024, "NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons", https://doi.org/10.18419/darus-3386, DaRUS, V1
Cloning and site-directed mutagenesis The gene of the catalytic, C-terminal domain of murine DNMT3C (amino acid residues 439-740 of P0DOY1) was obtained in E. coli codon optimized form from IDT Integrated DNA Technologies. The gene fragment was cloned with the StrataClone PCR Clo... |
Jan 12, 2024 - Amplicon based bisulfite NGS data
Jeltsch, Albert; Bashtrykov, Pavel; Rajaram, Nivethika, 2023, "NGS data related to Rajaram et al.: Development of super-specific epigenome editing by targeted allele-specific DNA methylation", https://doi.org/10.18419/darus-3581, DaRUS, V2
Method overview To achieve targeted ASM, transient transfection of the dCas9-10X SunTag-BFP, scFv-DNMT3A-3L-sfGFP, and sgRNA-DsRed plasmids was performed in HEK293 cells. Control experiments were conducted with a scrambled sgRNA that does not have a binding site in the human geno... |
Jan 10, 2024 - Amplicon based bisulfite NGS data
Jeltsch, Albert; Bashtrykov, Pavel; Albrecht, Claudia, 2024, "NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1", https://doi.org/10.18419/darus-3790, DaRUS, V1
Method overview For targeted DNA demethylation of the H19/IGF2 ICR1, HEK293 cells were transfected with two plasmids, one containing dCas9 fused to a SunTag with five repeats of the GCN4 peptide, separated by 22 aa long linkers, and scFv-fused TET1CD, as well as a GFP reporter pr... |
Dec 4, 2023 - Institute for Modelling and Simulation of Biomechanical Systems
Schmid, Laura; Klotz, Thomas; Röhrle, Oliver; Powers, Randall K.; Negro, Francesco; Yavuz, Utku S., 2023, "Replication Data for “Postinhibitory excitation in motoneurons can be facilitated by hyperpolarization-activated inward currents: a simulation study”", https://doi.org/10.18419/darus-3686, DaRUS, V1
This dataset contains spiketrains from experimental as well as simulated motoneurons that were analysed for the publication Postinhibitory excitation in motoneurons can be facilitated by hyperpolarization-activated inward currents: a simulation study. Abstract: Postinhibitory exc... |
Nov 20, 2023 - SPP2311: Ultrasound Neuromodulation
Werneck, Linda; Yildiz, Erdost; Han, Mertcan; Keip, Marc-Andre; Sitti, Metin; Ortiz, Michael, 2023, "Ion Flow Through Neural Ion Membrane: scripts and data", https://doi.org/10.18419/darus-3575, DaRUS, V1
The scripts and data are related to the numerical implementation of a quantitative model for ion flow through neural ion channels and a validation of the underlying single ion channel flow model for gramicidin A channels. The model is based on the Poisson-Nernst-Planck (PNP) equa... |
Jul 21, 2023 - HLRS-NUM-Biomechanics
Gebert, Johannes; Schneider, Ralf; Schnabel, Benjamin; Pelzer, Fabian; Helwig, Peter; Schenkengel, Jan-Peter, 2023, "Scanning Spongiosa: A set of Clinical Computed Tomography Scans of Human Femoral Heads", https://doi.org/10.18419/darus-3065, DaRUS, V1
Clinical computed tomography scans of 28 human femoral heads. They were explanted during total hip arthroplasty. |
Jun 21, 2023 - Neck Reflex Behavior in Driving Simulator Experiments
Kempter, Fabian; Lantella, Lorena; Stutzig, Norman; Fehr, Jörg; Siebert, Tobias, 2023, "Neck Reflex Behavior in Driving Simulator Experiments - Academic-Scale Simulator at ITM", https://doi.org/10.18419/darus-3000, DaRUS, V1
Neck movement and injury during a car crash is influenced by reflexes, strength, and flexibility. This data set contains in-vivo measurements of neck kinematics and reflexes as participants are rapidly accelerated while driving a mechanically simulated car. This data set includes... |
