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1 to 5 of 5 Results
Apr 11, 2024
Höpfl, Sebastian, 2024, "Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a", https://doi.org/10.18419/darus-3838, DaRUS, V1, UNF:6:az4wbAbWWcIbbLxQh/QPXA== [fileUNF]
This dataset contains the proposed sphingolipid rheostat model with mass-action kinetics and a proposed negative feedback from ceramide to its synthesis from Sphinganine. The model is written in the Systems Biology Markup Language (SBML) and with the experimental data, experiment...
Apr 9, 2024 - Mathematical modeling and simulation of cellular systems
Herrmann, Karl-Heinz; Zhao, Wan-Ting; Höpfl, Sebastian; Reichenbach, Jürgen R., 2024, "MRI based perfusion of rats with 60% PVL", https://doi.org/10.18419/darus-3878, DaRUS, V1, UNF:6:sQocf/P7vdAmWMQR6rEEJw== [fileUNF]
The study investigates in vivo liver perfusion in rats. Perfusion of ligated and non-ligated liver lobes of 25 rats was monitored via MRI. Rats were subjected to 60% Portal Vein Ligation (PVL). Experimentally, the left stem of the portal vein (supplying Left Median (LML) and Left...
Apr 8, 2024 - Mathematical modeling and simulation of cellular systems
Höpfl, Sebastian, 2024, "Bayesian Modeling of Time Series Data (BayModTS)", https://doi.org/10.18419/darus-3876, DaRUS, V1
BayModTS is a FAIR workflow for processing highly variable and sparse data. The code and results of the examples in the BayModTS paper are stored in this repository. A maintained version of BayModTS that can be applied to your personal applications can be found on Git Hub.
Apr 4, 2024
Mar 19, 2024
Höpfl, Sebastian, 2024, "Percentile Intervals in Bayesian Inference are Overconfident", https://doi.org/10.18419/darus-4068, DaRUS, V1
This dataset demonstrates the difference in calculating percentile Intervals as approximation for Highest Density Intervals (HDI) vs. Highest Posterior Density (HPD). This is demonstrated with extended partial liver resection data (ZeLeR-study, ethical vote: 2018-1246-Material)....
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