11 to 20 of 154 Results
Mar 28, 2024 - MD Simulations
Jeltsch, Albert; Schnee, Philipp; Pleiss, Jürgen; Weirich, Sara, 2024, "Additional data related to Weirich et al.: Discovery of new NSD2 non-histone substrates and design of a super-substrate", https://doi.org/10.18419/darus-3815, DaRUS, V1
This data collection contains additional data related to Weirich et al.: "Discovery of new NSD2 non-histone substrates and design of a super-substrate". This includes Modelled structures of NSD2 bound to different peptides Source data of the results of the MD analysis MD simulati... |
Mar 19, 2024 - Institute for Stochastics and Applications
Höpfl, Sebastian, 2024, "Percentile Intervals in Bayesian Inference are Overconfident", https://doi.org/10.18419/darus-4068, DaRUS, V1
This dataset demonstrates the difference in calculating percentile Intervals as approximation for Highest Density Intervals (HDI) vs. Highest Posterior Density (HPD). This is demonstrated with extended partial liver resection data (ZeLeR-study, ethical vote: 2018-1246-Material).... |
Jeltsch, Albert; Bashtrykov, Pavel; Dossmann, Leonie; Emperle, Max, 2024, "NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons", https://doi.org/10.18419/darus-3386, DaRUS, V1
Cloning and site-directed mutagenesis The gene of the catalytic, C-terminal domain of murine DNMT3C (amino acid residues 439-740 of P0DOY1) was obtained in E. coli codon optimized form from IDT Integrated DNA Technologies. The gene fragment was cloned with the StrataClone PCR Clo... |
Mikheev, Vladimir; Skukies, Rene; Ehinger, Benedikt, 2023, "Supplementary material: "The Art of Brainwaves: A Survey on Event-Related Potential Visualization Practices"", https://doi.org/10.18419/darus-3729, DaRUS, V2, UNF:6:+qePfVjlqif+DUSlAZSsrw== [fileUNF]
The purpose related to this dataset is to investigate the state of visualization in ERP (Event-Related Potential) research. The investigation was conducted through an online questionnaire administered via LimeSurvey Community Edition v5.4.7, hosted by the University of Stuttgart.... |
Feb 26, 2024 - Modelling, Simulation and Optimization for Agonist-Antagonist Myoneural Interface Surgeries
Homs Pons, Carme; Lautenschlager, Robin, 2024, "Replication Data for: Coupled Simulations and Parameter Inversion for Neural System and Electrophysiological Muscle Models", https://doi.org/10.18419/darus-4031, DaRUS, V1
This dataset allows to reproduce the results from the paper "Coupled Simulations and Parameter Inversion for Neural System and Electrophysiological Muscle Models" submitted to GAMM Mitteilungen in September 2023. Find more information about the structure of the dataset and the st... |
Feb 22, 2024Projects without PN Affiliation
The AMI is a limb amputation technique which aims to maintain the mechanical and neural feedback between agonist and antagonist muscle. We aim to develop a platform for in silico analysis which can provide insight to surgeons. For that we combine detailed multi-physics multi-scal... |
Jan 16, 2024 - Institute for Modelling and Simulation of Biomechanical Systems
Nadler, Tobias; Wolfen, Simon; Häufle, Daniel F. B.; Schmitt, Syn, 2024, "Technical specifications and details of the muscle-driven biorobotic arm ATARO", https://doi.org/10.18419/darus-3813, DaRUS, V1
ATARO is a bio-inspired arm robot with two degrees of freedom. Five artificial muscle-spring units (MSUs) are used for actuation. The MSUs, each consisting of a pneumatic artificial muscle (PAM) and a spring in series, mimic the characteristics of the human muscle-tendon complex.... |
Jan 12, 2024 - Amplicon based bisulfite NGS data
Jeltsch, Albert; Bashtrykov, Pavel; Rajaram, Nivethika, 2023, "NGS data related to Rajaram et al.: Development of super-specific epigenome editing by targeted allele-specific DNA methylation", https://doi.org/10.18419/darus-3581, DaRUS, V2
Method overview To achieve targeted ASM, transient transfection of the dCas9-10X SunTag-BFP, scFv-DNMT3A-3L-sfGFP, and sgRNA-DsRed plasmids was performed in HEK293 cells. Control experiments were conducted with a scrambled sgRNA that does not have a binding site in the human geno... |
Jan 10, 2024 - Amplicon based bisulfite NGS data
Jeltsch, Albert; Bashtrykov, Pavel; Albrecht, Claudia, 2024, "NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1", https://doi.org/10.18419/darus-3790, DaRUS, V1
Method overview For targeted DNA demethylation of the H19/IGF2 ICR1, HEK293 cells were transfected with two plasmids, one containing dCas9 fused to a SunTag with five repeats of the GCN4 peptide, separated by 22 aa long linkers, and scFv-fused TET1CD, as well as a GFP reporter pr... |
Jan 9, 2024 - Institute of Biochemistry and Technical Biochemistry
Häussler, Max, 2024, "Data for: 'EnzymeML-based modeling workflow: from raw data to kinetic parameters'", https://doi.org/10.18419/darus-3867, DaRUS, V1
Kinetic parameter estimates for small laccase (SLAC) catalyzed oxidation of ABTS, investigated across the temperature range between 25 °C and 45°C. This dataset contains the following files: Unprocessed absorption data from the respective enzyme assays (.txt) Derived calibration... |
