Institute for Stochastics and Applications

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31 to 40 of 47 Results

MRI based perfusion of rats with 60% PVL Apr 9, 2024 - Mathematical modeling and simulation of cellular systems Herrmann, Karl-Heinz; Zhao, Wan-Ting; Höpfl, Sebastian; Reichenbach, Jürgen R., 2024, "MRI based perfusion of rats with 60% PVL", https://doi.org/10.18419/DARUS-3878, DaRUS, V1, UNF:6:sQocf/P7vdAmWMQR6rEEJw== [fileUNF] The study investigates in vivo liver perfusion in rats. Perfusion of ligated and non-ligated liver lobes of 25 rats was monitored via MRI. Rats were subjected to 60% Portal Vein Ligation (PVL). Experimentally, the left stem of the portal vein (supplying Left Median (LML) and Left Lateral Lobe (LLL)) and the right stem to the Right Lobe (RL) were li...
Conversion_Mat_files_V2p1_darus.py Apr 9, 2024 - MRI based perfusion of rats with 60% PVL Python Source Code - 3.2 KB - MD5: 069279f5c3f88174e068fb86fead4956
MRI_voxel_data_converted_V21.tab Apr 9, 2024 - MRI based perfusion of rats with 60% PVL Tabular Data - 975.4 KB - 5 Variables, 22145 Observations - UNF:6:sQocf/P7vdAmWMQR6rEEJw==
PVL_ROI_V2.1.zip Apr 9, 2024 - MRI based perfusion of rats with 60% PVL ZIP Archive - 253.7 KB - MD5: ab623a378ff0a0b286e75ed76379cc92
Bayesian Modeling of Time Series Data (BayModTS) Apr 8, 2024 - Mathematical modeling and simulation of cellular systems Höpfl, Sebastian, 2024, "Bayesian Modeling of Time Series Data (BayModTS)", https://doi.org/10.18419/DARUS-3876, DaRUS, V1 BayModTS is a FAIR workflow for processing highly variable and sparse data. The code and results of the examples in the BayModTS paper are stored in this repository. A maintained version of BayModTS that can be applied to your personal applications can be found on Git Hub.
Influence of steatosis on drug metabolization dynamics in mice - validation broad prior.zip Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS) ZIP Archive - 810.7 MB - MD5: 71bbc489782cf6c1cde7d22ad272167a BayModTS results of the steatosis application using a broader prior for validation.
Influence of steatosis on drug metabolization dynamics in mice.zip Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS) ZIP Archive - 794.7 MB - MD5: 59ebfc89816bc3c3ce5c5dcea77237b4 PEtab files and results of the BayModTS steatosis application.
Influence of steatosis on drug metabolization - Pharmacokinetic model.zip Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS) ZIP Archive - 279.0 MB - MD5: bb20d18e0d920146e7e17cf273efc286 Application of the BayModTS workflow to the steatosis data, replacing the Retarded Transient Functions (RTFs) with a mechanistic pharmacokinetic model.
Postoperative liver regeneration after resection - validation broader prior.zip Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS) ZIP Archive - 228.2 MB - MD5: d0d04b3f5de2c6beb86e0ec050f9f87c BayModTS results of the liver regeneration example using a broader prior for validation. The data was generated under the ZeLeR-study (ethical vote: 2018- 1246-Material).
Postoperative liver regeneration after resection.zip Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS) ZIP Archive - 235.3 MB - MD5: a773c2789331928ce36e310682da4360 PEtab files and results of the BayModTS liver regeneration example. The data was generated under the ZeLeR-study (ethical vote: 2018- 1246-Material).

MRI based perfusion of rats with 60% PVL

Apr 9, 2024 - Mathematical modeling and simulation of cellular systems

Herrmann, Karl-Heinz; Zhao, Wan-Ting; Höpfl, Sebastian; Reichenbach, Jürgen R., 2024, "MRI based perfusion of rats with 60% PVL", https://doi.org/10.18419/DARUS-3878, DaRUS, V1, UNF:6:sQocf/P7vdAmWMQR6rEEJw== [fileUNF]

The study investigates in vivo liver perfusion in rats. Perfusion of ligated and non-ligated liver lobes of 25 rats was monitored via MRI. Rats were subjected to 60% Portal Vein Ligation (PVL). Experimentally, the left stem of the portal vein (supplying Left Median (LML) and Left Lateral Lobe (LLL)) and the right stem to the Right Lobe (RL) were li...

Conversion_Mat_files_V2p1_darus.py

Apr 9, 2024 - MRI based perfusion of rats with 60% PVL

Python Source Code - 3.2 KB -

MRI_voxel_data_converted_V21.tab

Apr 9, 2024 - MRI based perfusion of rats with 60% PVL

Tabular Data - 975.4 KB - 5 Variables, 22145 Observations -

PVL_ROI_V2.1.zip

Apr 9, 2024 - MRI based perfusion of rats with 60% PVL

ZIP Archive - 253.7 KB -

Bayesian Modeling of Time Series Data (BayModTS)

Apr 8, 2024 - Mathematical modeling and simulation of cellular systems

Höpfl, Sebastian, 2024, "Bayesian Modeling of Time Series Data (BayModTS)", https://doi.org/10.18419/DARUS-3876, DaRUS, V1

BayModTS is a FAIR workflow for processing highly variable and sparse data. The code and results of the examples in the BayModTS paper are stored in this repository. A maintained version of BayModTS that can be applied to your personal applications can be found on Git Hub.

Influence of steatosis on drug metabolization dynamics in mice - validation broad prior.zip

Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS)

ZIP Archive - 810.7 MB -

BayModTS results of the steatosis application using a broader prior for validation.

Influence of steatosis on drug metabolization dynamics in mice.zip

Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS)

ZIP Archive - 794.7 MB -

PEtab files and results of the BayModTS steatosis application.

Influence of steatosis on drug metabolization - Pharmacokinetic model.zip

Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS)

ZIP Archive - 279.0 MB -

Application of the BayModTS workflow to the steatosis data, replacing the Retarded Transient Functions (RTFs) with a mechanistic pharmacokinetic model.

Postoperative liver regeneration after resection - validation broader prior.zip

Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS)

ZIP Archive - 228.2 MB -

BayModTS results of the liver regeneration example using a broader prior for validation. The data was generated under the ZeLeR-study (ethical vote: 2018- 1246-Material).

Postoperative liver regeneration after resection.zip

Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS)

ZIP Archive - 235.3 MB -

PEtab files and results of the BayModTS liver regeneration example. The data was generated under the ZeLeR-study (ethical vote: 2018- 1246-Material).

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