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11 to 20 of 46 Results

get_boundaries_v9.ijm Mar 21, 2025 - DLC1 knockdown in EMT in MCF10A cells Unknown - 12.1 KB - MD5: e1a4c3d561bd5afb7abdf253deb07962 Script used for the IF images segmentation and analysis for classification into E-cad and N-Cad positive cells
MCMC_sampling_pypesto_workflow.py Mar 21, 2025 - DLC1 knockdown in EMT in MCF10A cells Python Source Code - 10.1 KB - MD5: 799aec9a1f707be058aceb3aee3f3bed Python script to perform MCMC sampling on the CBSD model using the PEtab files
Pypesto_Parameter_Estimation.py Mar 21, 2025 - DLC1 knockdown in EMT in MCF10A cells Python Source Code - 3.4 KB - MD5: 7c6b8e987ef2a9a70be164d7cc7473de Python script to calibrate the CBSD model using the PEtab files
Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a Apr 11, 2024 Höpfl, Sebastian, 2024, "Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a", https://doi.org/10.18419/DARUS-3838, DaRUS, V1, UNF:6:az4wbAbWWcIbbLxQh/QPXA== [fileUNF] This dataset contains the proposed sphingolipid rheostat model with mass-action kinetics and a proposed negative feedback from ceramide to its synthesis from Sphinganine. The model is written in the Systems Biology Markup Language (SBML) and with the experimental data, experimental conditions, parameters, and observables part of the PEtab paramter...
Simulation_Sphingolipid_rheostat_with_estimated_parameters.ipynb Apr 11, 2024 - Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a Jupyter Notebook - 883.0 KB - MD5: b7d7aa8ba9c53cc91fd1a89b37093801 File to simulate the PEtab file with the estimated paramters and to create the graphs shown in the paper
Sphingolipid_rheostat_Cer_activation_Cer.png Apr 11, 2024 - Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a PNG Image - 30.3 KB - MD5: 61fbc95ab20a230836d0215c66467a4c Visualization of the ceramide fits
Sphingolipid_rheostat_Cer_activation_Pypesto_Parameters.hdf5 Apr 11, 2024 - Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a Hierarchical Data Format - 2.3 MB - MD5: 888fc04bf67953d707da6f4739b6d7a8 Estimated parameters in hdf5 format
Sphingolipid_rheostat_Cer_activation_Pypesto_Parameters_optimization_dictionary.json Apr 11, 2024 - Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a JSON - 433 B - MD5: 60a86eb5ee0cee8adcb0caeeeb23f6f8 Inferred parameters of the rheostat model
Sphingolipid_rheostat_Cer_activation_S1P.png Apr 11, 2024 - Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a PNG Image - 28.0 KB - MD5: 95398fc849c74c43a81382e7e7826cd6 Visualization of the S1P fits
Sphingolipid_rheostat_Cer_activation_simulationData.tab Apr 11, 2024 - Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a Tabular Data - 3.4 KB - 7 Variables, 58 Observations - UNF:6:HQBqU3URE9FnG0Dn0xbRLw==

get_boundaries_v9.ijm

Mar 21, 2025 - DLC1 knockdown in EMT in MCF10A cells

Unknown - 12.1 KB -

Script used for the IF images segmentation and analysis for classification into E-cad and N-Cad positive cells

MCMC_sampling_pypesto_workflow.py

Mar 21, 2025 - DLC1 knockdown in EMT in MCF10A cells

Python Source Code - 10.1 KB -

Python script to perform MCMC sampling on the CBSD model using the PEtab files

Pypesto_Parameter_Estimation.py

Mar 21, 2025 - DLC1 knockdown in EMT in MCF10A cells

Python Source Code - 3.4 KB -

Python script to calibrate the CBSD model using the PEtab files

Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a

Apr 11, 2024

Höpfl, Sebastian, 2024, "Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a", https://doi.org/10.18419/DARUS-3838, DaRUS, V1, UNF:6:az4wbAbWWcIbbLxQh/QPXA== [fileUNF]

This dataset contains the proposed sphingolipid rheostat model with mass-action kinetics and a proposed negative feedback from ceramide to its synthesis from Sphinganine. The model is written in the Systems Biology Markup Language (SBML) and with the experimental data, experimental conditions, parameters, and observables part of the PEtab paramter...

Simulation_Sphingolipid_rheostat_with_estimated_parameters.ipynb

Apr 11, 2024 - Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a

Jupyter Notebook - 883.0 KB -

File to simulate the PEtab file with the estimated paramters and to create the graphs shown in the paper

Sphingolipid_rheostat_Cer_activation_Cer.png

Apr 11, 2024 - Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a

PNG Image - 30.3 KB -

Visualization of the ceramide fits

Sphingolipid_rheostat_Cer_activation_Pypesto_Parameters.hdf5

Apr 11, 2024 - Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a

Hierarchical Data Format - 2.3 MB -

Estimated parameters in hdf5 format

Sphingolipid_rheostat_Cer_activation_Pypesto_Parameters_optimization_dictionary.json

Apr 11, 2024 - Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a

JSON - 433 B -

Inferred parameters of the rheostat model

Sphingolipid_rheostat_Cer_activation_S1P.png

Apr 11, 2024 - Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a

PNG Image - 28.0 KB -

Visualization of the S1P fits

Sphingolipid_rheostat_Cer_activation_simulationData.tab

Apr 11, 2024 - Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a

Tabular Data - 3.4 KB - 7 Variables, 58 Observations -

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