Institute for Stochastics and Applications

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31 to 40 of 41 Results

PVL_ROI_V2.1.zip Apr 9, 2024 - MRI based perfusion of rats with 60% PVL ZIP Archive - 253.7 KB - MD5: ab623a378ff0a0b286e75ed76379cc92
Influence of steatosis on drug metabolization dynamics in mice - validation broad prior.zip Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS) ZIP Archive - 810.7 MB - MD5: 71bbc489782cf6c1cde7d22ad272167a BayModTS results of the steatosis application using a broader prior for validation.
Influence of steatosis on drug metabolization dynamics in mice.zip Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS) ZIP Archive - 794.7 MB - MD5: 59ebfc89816bc3c3ce5c5dcea77237b4 PEtab files and results of the BayModTS steatosis application.
Influence of steatosis on drug metabolization - Pharmacokinetic model.zip Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS) ZIP Archive - 279.0 MB - MD5: bb20d18e0d920146e7e17cf273efc286 Application of the BayModTS workflow to the steatosis data, replacing the Retarded Transient Functions (RTFs) with a mechanistic pharmacokinetic model.
Postoperative liver regeneration after resection - validation broader prior.zip Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS) ZIP Archive - 228.2 MB - MD5: d0d04b3f5de2c6beb86e0ec050f9f87c BayModTS results of the liver regeneration example using a broader prior for validation. The data was generated under the ZeLeR-study (ethical vote: 2018- 1246-Material).
Postoperative liver regeneration after resection.zip Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS) ZIP Archive - 235.3 MB - MD5: a773c2789331928ce36e310682da4360 PEtab files and results of the BayModTS liver regeneration example. The data was generated under the ZeLeR-study (ethical vote: 2018- 1246-Material).
Quantification of blood perfusion changes in liver lobes of rats after Portal Vein Ligation (PVL).zip Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS) ZIP Archive - 626.0 MB - MD5: 5145874ae49add4386038e858fb95685 PEtab files and results of the BayModTS MRI perfusion application.
Quantification of blood perfusion changes in liver lobes of rats after PVL - validation broader prior.zip Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS) ZIP Archive - 92.1 MB - MD5: 724d3fd3a3c59454a4c7124e722749f7 BayModTS results of the MRI perfusion application using a broader prior for validation.
liver_resection_bayesian_inference.zip Mar 19, 2024 - Percentile Intervals in Bayesian Inference are Overconfident ZIP Archive - 208.8 MB - MD5: 2a1c5c0fcc23335a335e7e3f3cfc37bf Bayesian Inference Results of the clinical dataset using BayModTS. Results include the posterior, the PEtab problem for inference. Further the results of the HPDR vs. PI comparison are included.
Plot_hpd_vd_hdi.py Mar 19, 2024 - Percentile Intervals in Bayesian Inference are Overconfident Python Source Code - 10.3 KB - MD5: 228226319e0fb9ba66c4bdf9c0457b01 Executable Pyhton file for the HPD vs HDI analysis. The posterior of the clinical data is calculated with the BayModTS workflow: https://github.com/Systems-Theory-in-Systems-Biology/BayModTS

PVL_ROI_V2.1.zip

Apr 9, 2024 - MRI based perfusion of rats with 60% PVL

ZIP Archive - 253.7 KB -

Influence of steatosis on drug metabolization dynamics in mice - validation broad prior.zip

Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS)

ZIP Archive - 810.7 MB -

BayModTS results of the steatosis application using a broader prior for validation.

Influence of steatosis on drug metabolization dynamics in mice.zip

Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS)

ZIP Archive - 794.7 MB -

PEtab files and results of the BayModTS steatosis application.

Influence of steatosis on drug metabolization - Pharmacokinetic model.zip

Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS)

ZIP Archive - 279.0 MB -

Application of the BayModTS workflow to the steatosis data, replacing the Retarded Transient Functions (RTFs) with a mechanistic pharmacokinetic model.

Postoperative liver regeneration after resection - validation broader prior.zip

Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS)

ZIP Archive - 228.2 MB -

BayModTS results of the liver regeneration example using a broader prior for validation. The data was generated under the ZeLeR-study (ethical vote: 2018- 1246-Material).

Postoperative liver regeneration after resection.zip

Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS)

ZIP Archive - 235.3 MB -

PEtab files and results of the BayModTS liver regeneration example. The data was generated under the ZeLeR-study (ethical vote: 2018- 1246-Material).

Quantification of blood perfusion changes in liver lobes of rats after Portal Vein Ligation (PVL).zip

Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS)

ZIP Archive - 626.0 MB -

PEtab files and results of the BayModTS MRI perfusion application.

Quantification of blood perfusion changes in liver lobes of rats after PVL - validation broader prior.zip

Apr 8, 2024 - Bayesian Modeling of Time Series Data (BayModTS)

ZIP Archive - 92.1 MB -

BayModTS results of the MRI perfusion application using a broader prior for validation.

liver_resection_bayesian_inference.zip

Mar 19, 2024 - Percentile Intervals in Bayesian Inference are Overconfident

ZIP Archive - 208.8 MB -

Bayesian Inference Results of the clinical dataset using BayModTS. Results include the posterior, the PEtab problem for inference. Further the results of the HPDR vs. PI comparison are included.

Plot_hpd_vd_hdi.py

Mar 19, 2024 - Percentile Intervals in Bayesian Inference are Overconfident

Python Source Code - 10.3 KB -

Executable Pyhton file for the HPD vs HDI analysis. The posterior of the clinical data is calculated with the BayModTS workflow: https://github.com/Systems-Theory-in-Systems-Biology/BayModTS

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