Institute of Biochemical Engineering

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2,671 to 2,680 of 2,988 Results

Figure5.tab Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies Tabular Data - 797 B - 4 Variables, 24 Observations - UNF:6:1v2ueH6QrpFch0T6vgGLbg== Data for the sigmoid fit to metabolite concentrations. Averaged and normalized analyte concentrations from organelle- or cytoplasm fractions over increasing digitonin concentration in fractionation buffer.
Figure6.tab Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies Tabular Data - 2.5 KB - 18 Variables, 20 Observations - UNF:6:mWkScrpAtXBjjTVXIe+lZQ== Averages of NSD concentrations in the cytoplasm and organelles. Measured over 6 days with different nutrient pulsing strategies applied on day 3: only medium (A); manganese, uridine, and fructose dissolved in medium (B); and manganese, uridine, and galactose dissolved in medium (C).
FigureS2.xlsx Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies MS Excel Spreadsheet - 13.2 KB - MD5: 85439b0a6f08828c717f5c1b06669bb4 Averaged cultivation parameters of CHO shaking flask cultivations. Parameters under three different nutrient-pulsing regimes. Data show condition (A) with only medium spiked, fructose spiked medium with manganese and uridine (B), and galactose spiked medium with manganese and uridine (C).
FigureS3.tab Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies Tabular Data - 1.3 KB - 14 Variables, 25 Observations - UNF:6:b19HAxpf2oV1MbnTDmcNfA== Averaged guanine oligophosphate levels. After concentration of fractions with lyophilization or evaporation.
FigureS4.tab Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies Tabular Data - 566 B - 10 Variables, 8 Observations - UNF:6:9dNfmJTzfmiv55W/T8fLWg== Averaged NSD levels After concentration of fractions with lyophilization or evaporation.
FigureS5_bot.xlsx Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies MS Excel Spreadsheet - 10.3 KB - MD5: c0ef33e5ba226512b89e8a9014aaedd7 Averaged relative glycan distributions expressed on antibodies at end of cultivations under pulsing condition with only medium spiked, fructose spiked medium with manganese and uridine (B) and galactose spiked medium with manganese and uridine (C).
FigureS5_top.tab Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies Tabular Data - 684 B - 10 Variables, 14 Observations - UNF:6:QZ+AKbnirkQ5g7gigP2AJA== Absolute concentration courses of produced glycans produced under pulsing condition with only medium spiked, fructose spiked medium with manganese and uridine (B) and galactose spiked medium with manganese and uridine (C).
Table2.tab Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies Tabular Data - 260 B - 4 Variables, 8 Observations - UNF:6:EaWo8Ka1e7CThlNkLrKx9A== Energy charge values for uridine- and guanosine nucleotides after lyophilisation or evaporation.
Table4.tab Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies Tabular Data - 144 B - 3 Variables, 6 Observations - UNF:6:rF2sZr737XwUUjJWay5rjw== Averaged metabolite concentration in subcellular metabolite fractions. Cellular metabolite concentration over increasing digitonin concentration in cytoplasm fractionation buffer. Fractions are cytoplasm and, organelles.
Data for: Semi-Continuous Biomanufacturing for Maximizing the Production of Complex Chemicals and Fuels: A Case Study on Amorpha-4,11-diene Oct 2, 2024 - Bioprocess Castillo-Saldarriaga, Carlos Rafael; Takors, Ralf, 2024, "Data for: Semi-Continuous Biomanufacturing for Maximizing the Production of Complex Chemicals and Fuels: A Case Study on Amorpha-4,11-diene", https://doi.org/10.18419/DARUS-4368, DaRUS, V1, UNF:6:f22Hsmd+PFJ4a4O1QNSxmg== [fileUNF] The DaRUS repository contains the raw data corresponding to the figures of the manuscript "Semi-Continuous Biomanufacturing for Maximizing the Production of Complex Chemicals and Fuels: A Case Study on Amorpha-4,11-diene". Biomanufacturing is emerging as a key technology for the sustainable production of chemicals, materials, and food ingredients u...

Figure5.tab

Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies

Tabular Data - 797 B - 4 Variables, 24 Observations -

Data for the sigmoid fit to metabolite concentrations. Averaged and normalized analyte concentrations from organelle- or cytoplasm fractions over increasing digitonin concentration in fractionation buffer.

Figure6.tab

Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies

Tabular Data - 2.5 KB - 18 Variables, 20 Observations -

Averages of NSD concentrations in the cytoplasm and organelles. Measured over 6 days with different nutrient pulsing strategies applied on day 3: only medium (A); manganese, uridine, and fructose dissolved in medium (B); and manganese, uridine, and galactose dissolved in medium (C).

FigureS2.xlsx

Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies

MS Excel Spreadsheet - 13.2 KB -

Averaged cultivation parameters of CHO shaking flask cultivations. Parameters under three different nutrient-pulsing regimes. Data show condition (A) with only medium spiked, fructose spiked medium with manganese and uridine (B), and galactose spiked medium with manganese and uridine (C).

FigureS3.tab

Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies

Tabular Data - 1.3 KB - 14 Variables, 25 Observations -

Averaged guanine oligophosphate levels. After concentration of fractions with lyophilization or evaporation.

FigureS4.tab

Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies

Tabular Data - 566 B - 10 Variables, 8 Observations -

Averaged NSD levels After concentration of fractions with lyophilization or evaporation.

FigureS5_bot.xlsx

Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies

MS Excel Spreadsheet - 10.3 KB -

Averaged relative glycan distributions expressed on antibodies at end of cultivations under pulsing condition with only medium spiked, fructose spiked medium with manganese and uridine (B) and galactose spiked medium with manganese and uridine (C).

FigureS5_top.tab

Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies

Tabular Data - 684 B - 10 Variables, 14 Observations -

Absolute concentration courses of produced glycans produced under pulsing condition with only medium spiked, fructose spiked medium with manganese and uridine (B) and galactose spiked medium with manganese and uridine (C).

Table2.tab

Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies

Tabular Data - 260 B - 4 Variables, 8 Observations -

Energy charge values for uridine- and guanosine nucleotides after lyophilisation or evaporation.

Table4.tab

Oct 28, 2024 - Assessing nucleotide sugar donors inside the Golgi apparatus as a prerequisite for unravelling culture impacts on glycoforms of antibodies

Tabular Data - 144 B - 3 Variables, 6 Observations -

Averaged metabolite concentration in subcellular metabolite fractions. Cellular metabolite concentration over increasing digitonin concentration in cytoplasm fractionation buffer. Fractions are cytoplasm and, organelles.

Data for: Semi-Continuous Biomanufacturing for Maximizing the Production of Complex Chemicals and Fuels: A Case Study on Amorpha-4,11-diene

Oct 2, 2024 - Bioprocess

Castillo-Saldarriaga, Carlos Rafael; Takors, Ralf, 2024, "Data for: Semi-Continuous Biomanufacturing for Maximizing the Production of Complex Chemicals and Fuels: A Case Study on Amorpha-4,11-diene", https://doi.org/10.18419/DARUS-4368, DaRUS, V1, UNF:6:f22Hsmd+PFJ4a4O1QNSxmg== [fileUNF]

The DaRUS repository contains the raw data corresponding to the figures of the manuscript "Semi-Continuous Biomanufacturing for Maximizing the Production of Complex Chemicals and Fuels: A Case Study on Amorpha-4,11-diene". Biomanufacturing is emerging as a key technology for the sustainable production of chemicals, materials, and food ingredients u...

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