Institute of Biochemical Engineering

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1 to 10 of 40 Results

Data for: “Single mutation in iolT1 in ptsG deficient C. glutamicum enables growth boost in xylose containing media” Sep 25, 2026 - Bioprocess Hofer, Katharina; Schwardmann, Lynn Sophie; Takors, Ralf; Wendisch, Volker F., 2026, "Data for: “Single mutation in iolT1 in ptsG deficient C. glutamicum enables growth boost in xylose containing media”", https://doi.org/10.18419/DARUS-5107, DaRUS, V1, UNF:6:S7u+87eRxfhpWexoakmamA== [fileUNF] The data uploaded here supplement the publication titled “Single mutation in iolT1 in ptsG deficient C. glutamicum enables growth boost in xylose containing media” Through rational strain design, continuous adaptive laboratory evolution (ALE) and whole-genome sequencing (WGS), we have identified a single point mutation in the iolT1 gene, leading to...
Data for: "Scale-down bioreactors reveal that prolonged mixing times deteriorate the performance of antibody-producing Chinese hamster ovary cells" Sep 24, 2026 - Mammalian Cell Culture Barczyk, Jonas; Lopez medina, Barbara; Teleki, Attila; Satzer, Peter; Rautenbach, Ryan; Schlüter, Michael; Takors, Ralf, 2026, "Data for: "Scale-down bioreactors reveal that prolonged mixing times deteriorate the performance of antibody-producing Chinese hamster ovary cells"", https://doi.org/10.18419/DARUS-6466, DaRUS, V1, UNF:6:lArxh/lys3TNx0/WEN5Rtg== [fileUNF] Raw data for the manuscript “Scale-down bioreactors reveal that prolonged mixing times deteriorate the performance of antibody-producing Chinese hamster ovary cells”. The work explores two approaches of prolonged mixing time in laboratory-scale vessels without changing the power input. Experiments in 3 liter bioreactors were performed with NISTCHO...
Data for: Ensuring Good Transferability from Pilot- to Large-Scale Optimized Biotech Bubble Column Designs Sep 21, 2026 - Modelling Link, Carolin; Bromley, Jason; Martin, Michael; Takors, Ralf, 2026, "Data for: Ensuring Good Transferability from Pilot- to Large-Scale Optimized Biotech Bubble Column Designs", https://doi.org/10.18419/DARUS-5576, DaRUS, V1 The DaRUS repository entails the simulation data for the publication: "Ensuring Good Transferability from Pilot- to Large-Scale Optimized Biotech Bubble Column Designs" Scaling biotechnology processes such as gas fermentation remains resource- and time-intensive, both experimentally and in modelling. To improve the efficiency of reactor-geometry op...
Data for: Simulating large-scale biotech bubble columns: Challenges and insights from the parcel approach Sep 21, 2026 - Modelling Link, Carolin; Puiman, Lars; Takors, Ralf, 2026, "Data for: Simulating large-scale biotech bubble columns: Challenges and insights from the parcel approach", https://doi.org/10.18419/DARUS-5525, DaRUS, V1 The DaRUS repository entails the simulation data for the publication "Simulating large-scale biotech bubble columns: Challenges and insights from the parcel approach" The growing industrial demand for economically attractive large-scale bioprocesses has increased the need for reliable and computationally feasible modelling approaches. Gas fermentat...
PANTABIO(Universität Stuttgart) Aug 19, 2026
SPP 2170 'InterZell': Understanding and Engineering Cell-Cell and Cell-Bioreactor Interactions Jul 22, 2026 - InterZell-Public Relation Rehnert, Martina; Takors, Ralf, 2026, "SPP 2170 'InterZell': Understanding and Engineering Cell-Cell and Cell-Bioreactor Interactions", https://doi.org/10.18419/DARUS-5201, DaRUS, V1 This video introduces the research focus of the DFG Priority Programme SPP 2170 'InterZell'. It presents the programme's interdisciplinary approach to investigating cell–cell and cell–bioreactor interactions and their role in bioprocess engineering. The programme brings together around 50 researchers in 10 collaborative projects to improve the unde...
InterZell-Public Relation(Universität Stuttgart) Jul 16, 2026SPP 2170 InterZell
Data and code for A Method for Optical Quantification of Local Oxygen Limitations in Multiphase Bioreactors May 26, 2026 - CHOLife_TUHH_LSP_tracking Rautenbach, Ryan, 2026, "Data and code for A Method for Optical Quantification of Local Oxygen Limitations in Multiphase Bioreactors", https://doi.org/10.18419/DARUS-5880, DaRUS, V1, UNF:6:WmPG67gXLTdskrCTPEzMqw== [fileUNF] This dataset contains the raw and processed experimental data, along with the analysis code, for the publication titled “A Method for Optical Quantification of Local Oxygen Limitations in Multiphase Bioreactors.” The data were obtained from optical measurements based on the reversible redox reaction of methylene blue in gas–liquid stirred tank bior...
Data and code for Enhancing Oxygen Mass Transfer in Unbaffled Stirred Tank Reactors through Counter-Rotating Coaxial Dual Impellers May 11, 2026 - CHOLife_TUHH_LSP_tracking Rautenbach, Ryan, 2026, "Data and code for Enhancing Oxygen Mass Transfer in Unbaffled Stirred Tank Reactors through Counter-Rotating Coaxial Dual Impellers", https://doi.org/10.18419/DARUS-5953, DaRUS, V1, UNF:6:iMm7TyF3JRtgyPtf6vSsVQ== [fileUNF] This dataset contains the experimental data, analysis scripts, and supplementary material associated with the publication “Enhancing Oxygen Mass Transfer in Unbaffled Stirred Tank Reactors through Counter-Rotating Coaxial Dual Impellers”. The repository includes oxygen mass transfer measurements, power input data, operating conditions, and image-ba...
Data for: Adaptive laboratory evolution of Saccharomyces cerevisiae enhances butyric acid tolerance and enables co-cultivation with Clostridium tyrobutyricum May 7, 2026 - SPP 2170 InterZell Oehlenschläger, Katharina; Bauschatz, Samira; Schepp, Emily; Holtmann, Dirk; Ulber, Roland, 2026, "Data for: Adaptive laboratory evolution of Saccharomyces cerevisiae enhances butyric acid tolerance and enables co-cultivation with Clostridium tyrobutyricum", https://doi.org/10.18419/DARUS-5936, DaRUS, V1, UNF:6:26/rWK7CknzNFS51szTvew== [fileUNF] This dataset includes all data used for analysis, calculations, and visualization of the results presented in this paper. The data are organized according to the figures in the main text. In addition, the Excel sheets contain brief background descriptions. The methods used to obtain the data are described in detail in the Materials and Methods sect...

Data for: “Single mutation in iolT1 in ptsG deficient C. glutamicum enables growth boost in xylose containing media”

Sep 25, 2026 - Bioprocess

Hofer, Katharina; Schwardmann, Lynn Sophie; Takors, Ralf; Wendisch, Volker F., 2026, "Data for: “Single mutation in iolT1 in ptsG deficient C. glutamicum enables growth boost in xylose containing media”", https://doi.org/10.18419/DARUS-5107, DaRUS, V1, UNF:6:S7u+87eRxfhpWexoakmamA== [fileUNF]

The data uploaded here supplement the publication titled “Single mutation in iolT1 in ptsG deficient C. glutamicum enables growth boost in xylose containing media” Through rational strain design, continuous adaptive laboratory evolution (ALE) and whole-genome sequencing (WGS), we have identified a single point mutation in the iolT1 gene, leading to...

Data for: "Scale-down bioreactors reveal that prolonged mixing times deteriorate the performance of antibody-producing Chinese hamster ovary cells"

Sep 24, 2026 - Mammalian Cell Culture

Barczyk, Jonas; Lopez medina, Barbara; Teleki, Attila; Satzer, Peter; Rautenbach, Ryan; Schlüter, Michael; Takors, Ralf, 2026, "Data for: "Scale-down bioreactors reveal that prolonged mixing times deteriorate the performance of antibody-producing Chinese hamster ovary cells"", https://doi.org/10.18419/DARUS-6466, DaRUS, V1, UNF:6:lArxh/lys3TNx0/WEN5Rtg== [fileUNF]

Raw data for the manuscript “Scale-down bioreactors reveal that prolonged mixing times deteriorate the performance of antibody-producing Chinese hamster ovary cells”. The work explores two approaches of prolonged mixing time in laboratory-scale vessels without changing the power input. Experiments in 3 liter bioreactors were performed with NISTCHO...

Data for: Ensuring Good Transferability from Pilot- to Large-Scale Optimized Biotech Bubble Column Designs

Sep 21, 2026 - Modelling

Link, Carolin; Bromley, Jason; Martin, Michael; Takors, Ralf, 2026, "Data for: Ensuring Good Transferability from Pilot- to Large-Scale Optimized Biotech Bubble Column Designs", https://doi.org/10.18419/DARUS-5576, DaRUS, V1

The DaRUS repository entails the simulation data for the publication: "Ensuring Good Transferability from Pilot- to Large-Scale Optimized Biotech Bubble Column Designs" Scaling biotechnology processes such as gas fermentation remains resource- and time-intensive, both experimentally and in modelling. To improve the efficiency of reactor-geometry op...

Data for: Simulating large-scale biotech bubble columns: Challenges and insights from the parcel approach

Sep 21, 2026 - Modelling

Link, Carolin; Puiman, Lars; Takors, Ralf, 2026, "Data for: Simulating large-scale biotech bubble columns: Challenges and insights from the parcel approach", https://doi.org/10.18419/DARUS-5525, DaRUS, V1

The DaRUS repository entails the simulation data for the publication "Simulating large-scale biotech bubble columns: Challenges and insights from the parcel approach" The growing industrial demand for economically attractive large-scale bioprocesses has increased the need for reliable and computationally feasible modelling approaches. Gas fermentat...

PANTABIO(Universität Stuttgart)

Aug 19, 2026

SPP 2170 'InterZell': Understanding and Engineering Cell-Cell and Cell-Bioreactor Interactions

Jul 22, 2026 - InterZell-Public Relation

Rehnert, Martina; Takors, Ralf, 2026, "SPP 2170 'InterZell': Understanding and Engineering Cell-Cell and Cell-Bioreactor Interactions", https://doi.org/10.18419/DARUS-5201, DaRUS, V1

This video introduces the research focus of the DFG Priority Programme SPP 2170 'InterZell'. It presents the programme's interdisciplinary approach to investigating cell–cell and cell–bioreactor interactions and their role in bioprocess engineering. The programme brings together around 50 researchers in 10 collaborative projects to improve the unde...

InterZell-Public Relation(Universität Stuttgart)

Jul 16, 2026SPP 2170 InterZell

Data and code for A Method for Optical Quantification of Local Oxygen Limitations in Multiphase Bioreactors

May 26, 2026 - CHOLife_TUHH_LSP_tracking

Rautenbach, Ryan, 2026, "Data and code for A Method for Optical Quantification of Local Oxygen Limitations in Multiphase Bioreactors", https://doi.org/10.18419/DARUS-5880, DaRUS, V1, UNF:6:WmPG67gXLTdskrCTPEzMqw== [fileUNF]

This dataset contains the raw and processed experimental data, along with the analysis code, for the publication titled “A Method for Optical Quantification of Local Oxygen Limitations in Multiphase Bioreactors.” The data were obtained from optical measurements based on the reversible redox reaction of methylene blue in gas–liquid stirred tank bior...

Data and code for Enhancing Oxygen Mass Transfer in Unbaffled Stirred Tank Reactors through Counter-Rotating Coaxial Dual Impellers

May 11, 2026 - CHOLife_TUHH_LSP_tracking

Rautenbach, Ryan, 2026, "Data and code for Enhancing Oxygen Mass Transfer in Unbaffled Stirred Tank Reactors through Counter-Rotating Coaxial Dual Impellers", https://doi.org/10.18419/DARUS-5953, DaRUS, V1, UNF:6:iMm7TyF3JRtgyPtf6vSsVQ== [fileUNF]

This dataset contains the experimental data, analysis scripts, and supplementary material associated with the publication “Enhancing Oxygen Mass Transfer in Unbaffled Stirred Tank Reactors through Counter-Rotating Coaxial Dual Impellers”. The repository includes oxygen mass transfer measurements, power input data, operating conditions, and image-ba...

Data for: Adaptive laboratory evolution of Saccharomyces cerevisiae enhances butyric acid tolerance and enables co-cultivation with Clostridium tyrobutyricum

May 7, 2026 - SPP 2170 InterZell

Oehlenschläger, Katharina; Bauschatz, Samira; Schepp, Emily; Holtmann, Dirk; Ulber, Roland, 2026, "Data for: Adaptive laboratory evolution of Saccharomyces cerevisiae enhances butyric acid tolerance and enables co-cultivation with Clostridium tyrobutyricum", https://doi.org/10.18419/DARUS-5936, DaRUS, V1, UNF:6:26/rWK7CknzNFS51szTvew== [fileUNF]

This dataset includes all data used for analysis, calculations, and visualization of the results presented in this paper. The data are organized according to the figures in the main text. In addition, the Excel sheets contain brief background descriptions. The methods used to obtain the data are described in detail in the Materials and Methods sect...

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