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Raw data for: The knowledge driven DBTL cycle provides mechanistic insights while optimising dopamine production in Escherichia coli
Apr 16, 2025
Hägele, Lorena; Takors, Ralf, 2025, "Raw data for: The knowledge driven DBTL cycle provides mechanistic insights while optimising dopamine production in Escherichia coli", https://doi.org/10.18419/DARUS-4714, DaRUS, V1
Dopamine is a promising organic compound with several key applications in emergency medicine, diagnosis and treatment of cancer, production of lithium anodes, and wastewater treatment. Since studies on in vivo dopamine production are limited, this study demonstrates the development and optimisation of a dopamine production strain by the help of the...
Getting the right clones in an automated manner: an alternative to sophisticated colony-picking robotics
Aug 2, 2024
Hägele, Lorena; Takors, Ralf, 2024, "Getting the right clones in an automated manner: an alternative to sophisticated colony-picking robotics", https://doi.org/10.18419/DARUS-4355, DaRUS, V1
In recent years, the Design-Build-Test-Learn (DBTL) cycle has become a key concept in strain engineering. Modern biofoundries enable automated DBTL cycling using robotic devices. However, both highly automated facilities and semi-automated facilities encounter bottlenecks in clone selection and screening. While fully automated biofoundries can take...
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