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Funding Information Agency: DFG Deposit Date: 2020 Subject: Medicine, Health and Life Sciences

1 to 8 of 8 Results

EHTM Code and Manual Oct 9, 2023 - Extended Hill-Type Muscle Material Model (EHTM) Nölle, Lennart; Lerge, Patrick; Martynenko, Oleksandr; Wochner, Isabell; Kempter, Fabian; Kleinbach, Christian; Schmitt, Syn; Fehr, Jörg, 2022, "EHTM Code and Manual", https://doi.org/10.18419/darus-1144, DaRUS, V2 This Dataset contains the implementation of the four element Extended Hill-type Muscle (EHTM) model with serial damping and eccentric force–velocity relation including Ca2+ dependent activation dynamics and internal methods for physiological muscle control for the finite-element...
Neck muscle data for Falling Heads: investigating reflexive responses to head-neck perturbations Apr 1, 2022 - Falling Heads Wochner, Isabell; Schmitt, Syn, 2022, "Neck muscle data for Falling Heads: investigating reflexive responses to head-neck perturbations", https://doi.org/10.18419/darus-1145, DaRUS, V1, UNF:6:x9+WHb9RUaJfQ9jJiNEQJw== [fileUNF] This dataset contains the neck muscle parameters for the user-defined Extended Hill Type Muscle Material as used in the publication paper "’Falling Heads’: investigating reflexive responses to head-neck perturbations" by Isabell Wochner, Lennart V. Nölle, Oleksandr V. Martynenko...
Trajectory Data for Falling Heads: investigating reflexive responses to head-neck perturbations Apr 1, 2022 - Falling Heads Wochner, Isabell, 2022, "Trajectory Data for Falling Heads: investigating reflexive responses to head-neck perturbations", https://doi.org/10.18419/darus-1132, DaRUS, V1, UNF:6:qCoJktHRm+8r61oAjbw9+w== [fileUNF] This dataset contains the extracted trajectories from the video data for 17 participants of the Falling Head experiment of the paper "’Falling Heads’: investigating reflexive responses to head-neck perturbations" by Isabell Wochner, Lennart V. Nölle, Oleksandr V. Martynenko and S...
EMG data for Falling Heads: investigating reflexive responses in active Human Body Models Apr 1, 2022 - Falling Heads Wochner, Isabell; Schmitt, Syn, 2022, "EMG data for Falling Heads: investigating reflexive responses in active Human Body Models", https://doi.org/10.18419/darus-1038, DaRUS, V1, UNF:6:qCoJktHRm+8r61oAjbw9+w== [fileUNF] This dataset contains the raw electromyographic (EMG) data for 17 participants of the Falling Head experiment of the paper "’Falling Heads’: investigating reflexive responses to head-neck perturbations" by Isabell Wochner, Lennart V. Nölle, Oleksandr V. Martynenko and Syn Schmitt...
Deep enzymology data related to Dukatz et al.: Complex DNA sequence readout mechanisms of the DNMT3B DNA methyltransferase. Sep 1, 2020 - Amplicon based bisulfite NGS data Jeltsch, Albert; Bashtrykov, Pavel; Dukatz, Michael; Adam, Sabrina, 2020, "Deep enzymology data related to Dukatz et al.: Complex DNA sequence readout mechanisms of the DNMT3B DNA methyltransferase.", https://doi.org/10.18419/darus-815, DaRUS, V3 Experimental procedures: Libraries of double stranded DNA substrates with CpG, CpH or CpN sites in randomized sequence context were methlyated by DNMT3B. Reactions were stopped by shock freezing in liquid nitrogen, then treated with proteinase K for 2 hours. Afterwards, the DNA w...
Deep enzymology data related to Gao et al.: Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms Jan 30, 2020 - Amplicon based bisulfite NGS data Jeltsch, Albert; Bashtrykov, Pavel; Emperle, Max; Adam, Sabrina; Dukatz, Michael, 2020, "Deep enzymology data related to Gao et al.: Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms", https://doi.org/10.18419/darus-627, DaRUS, V1 Experimental procedures: Libraries of double stranded DNA substrates with CpG, CpH or CpN sites in randomized sequence context were methlyated by DNMT3A or DNMT3B. Reactions were stopped by shock freezing in liquid nitrogen, then treated with proteinase K for 2 hours. Afterwards,...
Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation Jan 30, 2020 - Amplicon based bisulfite NGS data Jeltsch, Albert; Bashtrykov, Pavel; Adam, Sabrina, 2020, "Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation", https://doi.org/10.18419/darus-629, DaRUS, V1 Methylation of long hemimethylated DNA substrates: Methylation of the 349 bp long hemimethylated substrate with DNMT1 was carried out in 1X methylation buffer (100 mM HEPES, 1 mM EDTA, 0.5 mM DTT, 0.1 mg/mL BSA, pH 7.2 with KOH) in the presence of 1 mM AdoMet. For the methylation...
Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation Jan 30, 2020 - Amplicon based bisulfite NGS data Jeltsch, Albert; Bashtrykov, Pavel; Adam, Sabrina, 2020, "Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation", https://doi.org/10.18419/darus-628, DaRUS, V1 Methylation of random flank substrates: Libraries of double stranded DNA substrates with unmethylated or hemimethylated CpG sites in randomized sequence context were methlyated by DNMT1. Reactions were stopped by shock freezing in liquid nitrogen, then treated with proteinase K f...

EHTM Code and Manual

Oct 9, 2023 - Extended Hill-Type Muscle Material Model (EHTM)

Nölle, Lennart; Lerge, Patrick; Martynenko, Oleksandr; Wochner, Isabell; Kempter, Fabian; Kleinbach, Christian; Schmitt, Syn; Fehr, Jörg, 2022, "EHTM Code and Manual", https://doi.org/10.18419/darus-1144, DaRUS, V2

This Dataset contains the implementation of the four element Extended Hill-type Muscle (EHTM) model with serial damping and eccentric force–velocity relation including Ca2+ dependent activation dynamics and internal methods for physiological muscle control for the finite-element...

Neck muscle data for Falling Heads: investigating reflexive responses to head-neck perturbations

Apr 1, 2022 - Falling Heads

Wochner, Isabell; Schmitt, Syn, 2022, "Neck muscle data for Falling Heads: investigating reflexive responses to head-neck perturbations", https://doi.org/10.18419/darus-1145, DaRUS, V1, UNF:6:x9+WHb9RUaJfQ9jJiNEQJw== [fileUNF]

This dataset contains the neck muscle parameters for the user-defined Extended Hill Type Muscle Material as used in the publication paper "’Falling Heads’: investigating reflexive responses to head-neck perturbations" by Isabell Wochner, Lennart V. Nölle, Oleksandr V. Martynenko...

Trajectory Data for Falling Heads: investigating reflexive responses to head-neck perturbations

Apr 1, 2022 - Falling Heads

Wochner, Isabell, 2022, "Trajectory Data for Falling Heads: investigating reflexive responses to head-neck perturbations", https://doi.org/10.18419/darus-1132, DaRUS, V1, UNF:6:qCoJktHRm+8r61oAjbw9+w== [fileUNF]

This dataset contains the extracted trajectories from the video data for 17 participants of the Falling Head experiment of the paper "’Falling Heads’: investigating reflexive responses to head-neck perturbations" by Isabell Wochner, Lennart V. Nölle, Oleksandr V. Martynenko and S...

EMG data for Falling Heads: investigating reflexive responses in active Human Body Models

Apr 1, 2022 - Falling Heads

Wochner, Isabell; Schmitt, Syn, 2022, "EMG data for Falling Heads: investigating reflexive responses in active Human Body Models", https://doi.org/10.18419/darus-1038, DaRUS, V1, UNF:6:qCoJktHRm+8r61oAjbw9+w== [fileUNF]

This dataset contains the raw electromyographic (EMG) data for 17 participants of the Falling Head experiment of the paper "’Falling Heads’: investigating reflexive responses to head-neck perturbations" by Isabell Wochner, Lennart V. Nölle, Oleksandr V. Martynenko and Syn Schmitt...

Deep enzymology data related to Dukatz et al.: Complex DNA sequence readout mechanisms of the DNMT3B DNA methyltransferase.

Sep 1, 2020 - Amplicon based bisulfite NGS data

Jeltsch, Albert; Bashtrykov, Pavel; Dukatz, Michael; Adam, Sabrina, 2020, "Deep enzymology data related to Dukatz et al.: Complex DNA sequence readout mechanisms of the DNMT3B DNA methyltransferase.", https://doi.org/10.18419/darus-815, DaRUS, V3

Experimental procedures: Libraries of double stranded DNA substrates with CpG, CpH or CpN sites in randomized sequence context were methlyated by DNMT3B. Reactions were stopped by shock freezing in liquid nitrogen, then treated with proteinase K for 2 hours. Afterwards, the DNA w...

Deep enzymology data related to Gao et al.: Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms

Jan 30, 2020 - Amplicon based bisulfite NGS data

Jeltsch, Albert; Bashtrykov, Pavel; Emperle, Max; Adam, Sabrina; Dukatz, Michael, 2020, "Deep enzymology data related to Gao et al.: Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms", https://doi.org/10.18419/darus-627, DaRUS, V1

Experimental procedures: Libraries of double stranded DNA substrates with CpG, CpH or CpN sites in randomized sequence context were methlyated by DNMT3A or DNMT3B. Reactions were stopped by shock freezing in liquid nitrogen, then treated with proteinase K for 2 hours. Afterwards,...

Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation

Jan 30, 2020 - Amplicon based bisulfite NGS data

Jeltsch, Albert; Bashtrykov, Pavel; Adam, Sabrina, 2020, "Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation", https://doi.org/10.18419/darus-629, DaRUS, V1

Methylation of long hemimethylated DNA substrates: Methylation of the 349 bp long hemimethylated substrate with DNMT1 was carried out in 1X methylation buffer (100 mM HEPES, 1 mM EDTA, 0.5 mM DTT, 0.1 mg/mL BSA, pH 7.2 with KOH) in the presence of 1 mM AdoMet. For the methylation...

Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation

Jan 30, 2020 - Amplicon based bisulfite NGS data

Methylation of random flank substrates: Libraries of double stranded DNA substrates with unmethylated or hemimethylated CpG sites in randomized sequence context were methlyated by DNMT1. Reactions were stopped by shock freezing in liquid nitrogen, then treated with proteinase K f...

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