Department of Molecular Biochemistry

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831 to 840 of 850 Results

Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation Jan 30, 2020 - Amplicon based bisulfite NGS data Jeltsch, Albert; Bashtrykov, Pavel; Adam, Sabrina, 2020, "Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation", https://doi.org/10.18419/DARUS-629, DaRUS, V1 Methylation of long hemimethylated DNA substrates: Methylation of the 349 bp long hemimethylated substrate with DNMT1 was carried out in 1X methylation buffer (100 mM HEPES, 1 mM EDTA, 0.5 mM DTT, 0.1 mg/mL BSA, pH 7.2 with KOH) in the presence of 1 mM AdoMet. For the methylation reactions, mixtures containing different DNMT1 concentrations were pr...
hemimethylated lower strand.txt Jan 30, 2020 - Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation Plain Text - 1.1 MB - MD5: 4f5230094402e35dcfa1156546e57356 Data
hemimethylated upper strand.txt Jan 30, 2020 - Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation Plain Text - 3.8 MB - MD5: 6c25bbddae74c0352e565131ddc08da0 Data
readme_long_hm_substrate.pdf Jan 30, 2020 - Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation Adobe PDF - 532.3 KB - MD5: acc89345fa8b47ac376f932831cfc1bd Documentation Additional information
Repeat 1, 10 min.txt Jan 30, 2020 - Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation Plain Text - 26.4 MB - MD5: 91487f57d341a552813d1554427bb28c Data
Repeat 1, 1 min.txt Jan 30, 2020 - Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation Plain Text - 19.7 MB - MD5: 060d542d77d97e23702c219e92b21b96 Data
Repeat 1, 30 min.txt Jan 30, 2020 - Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation Plain Text - 24.7 MB - MD5: af247d9d6c4f05fd2f347711fe4367f7 Data
Repeat 1, 3 min.txt Jan 30, 2020 - Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation Plain Text - 19.5 MB - MD5: 68d13d33953be0cb1ebdf71e001011dc Data
Repeat 2, 10 min.txt Jan 30, 2020 - Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation Plain Text - 21.9 MB - MD5: 1e7c9ca8bdd596dac639120663c518ac Data
Repeat 2, 1 min.txt Jan 30, 2020 - Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation Plain Text - 19.8 MB - MD5: f3d2328343d546c1c52bb3d05bd8a0d1 Data

Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation

Jan 30, 2020 - Amplicon based bisulfite NGS data

Jeltsch, Albert; Bashtrykov, Pavel; Adam, Sabrina, 2020, "Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation", https://doi.org/10.18419/DARUS-629, DaRUS, V1

Methylation of long hemimethylated DNA substrates: Methylation of the 349 bp long hemimethylated substrate with DNMT1 was carried out in 1X methylation buffer (100 mM HEPES, 1 mM EDTA, 0.5 mM DTT, 0.1 mg/mL BSA, pH 7.2 with KOH) in the presence of 1 mM AdoMet. For the methylation reactions, mixtures containing different DNMT1 concentrations were pr...

hemimethylated lower strand.txt

Jan 30, 2020 - Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation

Plain Text - 1.1 MB -

Data

hemimethylated upper strand.txt

Jan 30, 2020 - Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation

Plain Text - 3.8 MB -

Data

readme_long_hm_substrate.pdf

Jan 30, 2020 - Deep enzymology data related to Adam et al.: DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation

Adobe PDF - 532.3 KB -

Documentation