Department of Molecular Biochemistry

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491 to 500 of 831 Results

model_NSD2-WT.pdb Mar 14, 2023 - Additional data related to Khella et al.: The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation application/vnd.palm - 182.6 KB - MD5: e81776ea712f1ba8437f7ff1c8cf740b
Movie 1 - NSD2 T1150A SAM sMD.mp4 Mar 14, 2023 - Additional data related to Khella et al.: The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation MPEG-4 Video - 33.8 MB - MD5: e374e9d928bb3187773f168726b6834e Example of a successful docking of AdoMet to the NSD2 T1150A – H3K36me2 peptide complex.
NSD2 MD Data 2.xlsx Mar 14, 2023 - Additional data related to Khella et al.: The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation MS Excel Spreadsheet - 901.0 KB - MD5: 26ff262c131210882b420c1b92b941f9 Source data of the results of the MD analysis.
POVME3_input.ini Mar 14, 2023 - Additional data related to Khella et al.: The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation Unknown - 645 B - MD5: baa32dae890c6be1e35fb135e46601b1 Input parameters for POVME3 volume calculation
Production_NSD2-T1150A_sMD.py Mar 14, 2023 - Additional data related to Khella et al.: The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation Python Source Code - 20.3 KB - MD5: 3e91fe1f6e0aaf8f80146b8cc2bdfe9e Python script for the production of SAM-enzyme association sMD simulation trajectories.
Production_NSD2-T1150_complexed_SAM.py Mar 14, 2023 - Additional data related to Khella et al.: The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation Python Source Code - 14.8 KB - MD5: ca93ed0898dd704f624ca23aef594cf2 Python script for the production of enzyme-SAM complex MD simulation trajectories.
README.pdf Mar 14, 2023 - Additional data related to Khella et al.: The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation Adobe PDF - 120.1 KB - MD5: 9b2e5f6281fc434a6d06535a5ce3677c Description of the python scripts provided in this repository. Instructions for use, installation and outcome.
SAM.pdb Mar 14, 2023 - Additional data related to Khella et al.: The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation application/vnd.palm - 5.0 KB - MD5: 8f8bfe32179ce5e4cdf3f1cee3d01e8f
SAM-sMD.pdb Mar 14, 2023 - Additional data related to Khella et al.: The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation application/vnd.palm - 5.0 KB - MD5: f7bdbe29edd4db19b6d1928185037563
SAM.xml Mar 14, 2023 - Additional data related to Khella et al.: The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation XML - 20.9 KB - MD5: 8504b192cebc39de3edb5595d94cd0e4 Parameters for the cofactor SAM (AdoMet).

model_NSD2-WT.pdb

Mar 14, 2023 - Additional data related to Khella et al.: The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation

application/vnd.palm - 182.6 KB -

Movie 1 - NSD2 T1150A SAM sMD.mp4

Mar 14, 2023 - Additional data related to Khella et al.: The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation

MPEG-4 Video - 33.8 MB -

Example of a successful docking of AdoMet to the NSD2 T1150A – H3K36me2 peptide complex.

NSD2 MD Data 2.xlsx

Mar 14, 2023 - Additional data related to Khella et al.: The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation

MS Excel Spreadsheet - 901.0 KB -

Source data of the results of the MD analysis.

POVME3_input.ini