Department of Molecular Biochemistry

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171 to 180 of 852 Results

sequencing data file_after_revision_Nov_2023_v2.xlsx Jan 12, 2024 - NGS data related to Rajaram et al.: Development of super-specific epigenome editing by targeted allele-specific DNA methylation MS Excel Spreadsheet - 29.7 KB - MD5: d6ddba1c0d33a89731b57212cc659179 Information about connections of experiments and sequencing data
NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1 Jan 10, 2024 - Amplicon based bisulfite NGS data Jeltsch, Albert; Bashtrykov, Pavel; Albrecht, Claudia, 2024, "NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1", https://doi.org/10.18419/DARUS-3790, DaRUS, V1 Method overview For targeted DNA demethylation of the H19/IGF2 ICR1, HEK293 cells were transfected with two plasmids, one containing dCas9 fused to a SunTag with five repeats of the GCN4 peptide, separated by 22 aa long linkers, and scFv-fused TET1CD, as well as a GFP reporter protein. The second plasmid encodes five sgRNAs targeting the ICR1 and a...
10a_1.fq.gz Jan 10, 2024 - NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1 Gzip Archive - 57.5 MB - MD5: 5011f6791cb689554ae334baa1918394
10a_2.fq.gz Jan 10, 2024 - NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1 Gzip Archive - 66.3 MB - MD5: 179511fa9bda9093f74635aceafad658
10b_2.fq.gz Jan 10, 2024 - NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1 Gzip Archive - 229.7 MB - MD5: 51c57d1f4272c2fa4779b3c596366aca
11a_1.fq.gz Jan 10, 2024 - NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1 Gzip Archive - 49.3 MB - MD5: 68936a7fd6cac43cd46a76b74c678c5d
11a_2.fq.gz Jan 10, 2024 - NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1 Gzip Archive - 58.4 MB - MD5: 9931bec183b91255eea8ab7c7c0965d9
11b_1.fq.gz Jan 10, 2024 - NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1 Gzip Archive - 172.1 MB - MD5: b1f2cc6e21f4b3a79dab4bd27a8b8b66
11b_2.fq.gz Jan 10, 2024 - NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1 Gzip Archive - 202.7 MB - MD5: 7993fabe38431b573aa1ba315380437d
12a_1.fq.gz Jan 10, 2024 - NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1 Gzip Archive - 46.2 MB - MD5: 58141477909cac5dda5823cbe7ef00a1

sequencing data file_after_revision_Nov_2023_v2.xlsx

Jan 12, 2024 - NGS data related to Rajaram et al.: Development of super-specific epigenome editing by targeted allele-specific DNA methylation

MS Excel Spreadsheet - 29.7 KB -

Information about connections of experiments and sequencing data

NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1

Jan 10, 2024 - Amplicon based bisulfite NGS data

Jeltsch, Albert; Bashtrykov, Pavel; Albrecht, Claudia, 2024, "NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1", https://doi.org/10.18419/DARUS-3790, DaRUS, V1

Method overview For targeted DNA demethylation of the H19/IGF2 ICR1, HEK293 cells were transfected with two plasmids, one containing dCas9 fused to a SunTag with five repeats of the GCN4 peptide, separated by 22 aa long linkers, and scFv-fused TET1CD, as well as a GFP reporter protein. The second plasmid encodes five sgRNAs targeting the ICR1 and a...

10a_1.fq.gz

Jan 10, 2024 - NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1

Gzip Archive - 57.5 MB -

10a_2.fq.gz

Jan 10, 2024 - NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1

Gzip Archive - 66.3 MB -

10b_2.fq.gz

Jan 10, 2024 - NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1

Gzip Archive - 229.7 MB -

11a_1.fq.gz

Jan 10, 2024 - NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1

Gzip Archive - 49.3 MB -