Department of Molecular Biochemistry

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161 to 170 of 852 Results

DNMT3C wt_R3_CN.tabular Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons Unknown - 9.1 MB - MD5: 1f5073181df4e91708266d494738bc77
DNMT3C wt_R4_CG.tabular Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons Unknown - 12.0 MB - MD5: c2ca0f8d18f8ead3d5cb56b8747ce5ec
DNMT3C wt_R4_CN.tabular Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons Unknown - 10.9 MB - MD5: 5d4a36bca752cc6c9f840133bd8be60c
DNMT3C wt_R5_CG.tabular Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons Unknown - 11.1 MB - MD5: 566adf593d9dc3c110af9804a38c67e5
DNMT3C wt_R5_CN.tabular Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons Unknown - 11.5 MB - MD5: 73e0d4bb5cfe4d8e2d4d55f9f18094a4
DNMT3C wt_R6_CG.tabular Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons Unknown - 8.9 MB - MD5: b18fcbd3ca9b75707ce0da0fd1f9d6df
DNMT3C wt_R6_CN.tabular Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons Unknown - 8.9 MB - MD5: b491e133998e0af6394a0a34c36b1abd
DNMT3C wt_R7_CG.tabular Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons Unknown - 5.9 MB - MD5: 3658de0085cae3ca8cb2fc4352d0137a
readme_random_flank_substrate.pdf Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons Adobe PDF - 88.9 KB - MD5: 87197499fe59431b4dccba8501193e04
NGS data related to Rajaram et al.: Development of super-specific epigenome editing by targeted allele-specific DNA methylation Jan 12, 2024 - Amplicon based bisulfite NGS data Jeltsch, Albert; Bashtrykov, Pavel; Rajaram, Nivethika, 2023, "NGS data related to Rajaram et al.: Development of super-specific epigenome editing by targeted allele-specific DNA methylation", https://doi.org/10.18419/DARUS-3581, DaRUS, V2 Method overview To achieve targeted ASM, transient transfection of the dCas9-10X SunTag-BFP, scFv-DNMT3A-3L-sfGFP, and sgRNA-DsRed plasmids was performed in HEK293 cells. Control experiments were conducted with a scrambled sgRNA that does not have a binding site in the human genome. Initial studies showed that cells positive for all three plasmids...

DNMT3C wt_R3_CN.tabular

Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons

Unknown - 9.1 MB -

DNMT3C wt_R4_CG.tabular

Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons

Unknown - 12.0 MB -

DNMT3C wt_R4_CN.tabular

Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons

Unknown - 10.9 MB -

DNMT3C wt_R5_CG.tabular

Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons

Unknown - 11.1 MB -

DNMT3C wt_R5_CN.tabular

Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons

Unknown - 11.5 MB -

DNMT3C wt_R6_CG.tabular

Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons

Unknown - 8.9 MB -

DNMT3C wt_R6_CN.tabular

Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons

Unknown - 8.9 MB -

DNMT3C wt_R7_CG.tabular

Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons

Unknown - 5.9 MB -

readme_random_flank_substrate.pdf

Mar 4, 2024 - NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons

Adobe PDF - 88.9 KB -

NGS data related to Rajaram et al.: Development of super-specific epigenome editing by targeted allele-specific DNA methylation

Jan 12, 2024 - Amplicon based bisulfite NGS data

Jeltsch, Albert; Bashtrykov, Pavel; Rajaram, Nivethika, 2023, "NGS data related to Rajaram et al.: Development of super-specific epigenome editing by targeted allele-specific DNA methylation", https://doi.org/10.18419/DARUS-3581, DaRUS, V2

Method overview To achieve targeted ASM, transient transfection of the dCas9-10X SunTag-BFP, scFv-DNMT3A-3L-sfGFP, and sgRNA-DsRed plasmids was performed in HEK293 cells. Control experiments were conducted with a scrambled sgRNA that does not have a binding site in the human genome. Initial studies showed that cells positive for all three plasmids...

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