41 to 50 of 154 Results
Jeltsch, Albert; Bashtrykov, Pavel; Adam, Sabrina, 2023, "NGS data related to Adam et al.: On the accuracy of the epigenetic copy machine - comprehensive specificity analysis of the DNMT1 DNA methyltransferase", https://doi.org/10.18419/darus-3334, DaRUS, V2, UNF:6:ERMvcNuV8nq+mI9Q5Xu53A== [fileUNF]
Expression and purification of DNMT1 for biochemical work Full length murine DNMT1 (UniProtKB P13864) was overexpressed and purified as described (Adam, et al. 2020) using the Bac-to-Bac baculovirus expression system (Invitrogen). The expression construct of the DNMT1 with mutate... |
Apr 27, 2023 - Supporting Information for Publications
Fullstone, Gavin, 2023, "Supporting Information for Rapid Particle-based Simulations of Cellular Signalling with the FLAME-accelerated Signalling Tool (FaST) and GPUs", https://doi.org/10.18419/darus-2175, DaRUS, V1
This folder contains expected inputs and outputs from the example model used in the paper "Rapid Particle-based Simulations of Cellular Signalling with the FLAME-accelerated Signalling Tool (FaST) and GPUs". These can be used to troubleshoot unexpected problems. |
Jeltsch, Albert; Schnee, Philipp; Saad, Mina; Weirich, Sara; Pleiss, Jürgen; Bashtrykov, Pavel, 2023, "Additional data related to Khella et al.: The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation", https://doi.org/10.18419/darus-3263, DaRUS, V1
This data collection contains additional data related to Khella et al.: "The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation". This includes Movie 1: Example of a successful docking of AdoMet to the NSD2 T1150A - H3K36me2 pepti... |
Mar 9, 2023 - PN 3-11
Degen, Morris; Santos, José Carlos; Pluhackova, Kristyna; Cebrero, Gonzalo; Ramos, Saray; Jankevicius, Gytis; Hartenian, Ella; Guillerm, Undina; Mari, Stefania A.; Kohl, Bastian; Müller, Daniel J.; Schanda, Paul; Maier, Timm; Perez, Camilo; Sieben, Christian; Broz, Petr; Hiller, Sebastian, 2023, "Supplementary material for 'Structural basis for ninjurin-1 mediated plasma membrane rupture in lytic cell death'", https://doi.org/10.18419/darus-3373, DaRUS, V1
Eukaryotic cells can undergo different forms of programmed cell death, many of which culminate in plasma membrane rupture (PMR) as the defining terminal event. PMR was long thought to be driven by osmotic pressure, until it was recently shown to be in many cases an active process... |
Jan 30, 2023 - PN 7-6
Kneifl, Jonas; Rosin, David; Avci, Okan; Röhrle, Oliver; Fehr, Jörg, 2023, "Continuum-mechanical Forward Simulation Results of a Human Upper-limb Model Under Varying Muscle Activations", https://doi.org/10.18419/darus-3302, DaRUS, V1
This dataset provides simulation results from a high-fidelity human upper-arm finite element model under varying muscle activations and an example script to load the data. The upper arm model consists of the bones of the radius and ulna for the forearm and the humerus for the upp... |
Jan 10, 2023 - Department of Biochemistry
Jeltsch, Albert; Broche, Julian, 2023, "Gene expression data related to Broche et al.: "Genome-wide deposition of 6-methyladenine in human DNA reduces the viability of HEK293 cells and directly influences gene expression"", https://doi.org/10.18419/darus-2813, DaRUS, V1
In the publication "Genome-wide deposition of 6-methyladenine in human DNA reduces the viability of HEK293 cells and directly influences gene expression" bacterial DNA-adenine N6-Methyltransferases were expressed in human HEK293 cells. Cell proliferation and gene expression were... |
Dec 16, 2022 - demoa
Wochner, Isabell; Schmitt, Syn, 2022, "MPC/OC Code for: Learning with Muscles: Benefits for Data-Efficiency and Robustness in Anthropomorphic Tasks", https://doi.org/10.18419/darus-3268, DaRUS, V1
This code allows you reproduce the optimal control and model predictive control results of the paper: "Learning with Muscles: Benefits for Data-Efficiency and Robustness in Anthropomorphic Tasks" by Isabell Wochner, Pierre Schumacher, Georg Martius, Dieter Büchler, Syn Schmitt an... |
Schmitt, Syn, 2022, "demoa-base: a biophysics simulator for muscle-driven motion", https://doi.org/10.18419/darus-2550, DaRUS, V4
For more information, such as installation, requirements and user guide, please see the demoa-manual.pdf |
Nov 21, 2022 - SFB-TRR 161 D04 "Quantitative Aspects of Immersive Analytics for the Life Sciences"
Klein, Karsten; Garkov, Dimitar; Rütschlin, Sina; Böttcher, Thomas; Schreiber, Falk, 2022, "QSDB - a graphical Quorum Sensing Database: VANTED add-on source code", https://doi.org/10.18419/darus-3242, DaRUS, V1
The add-on had been designed for the VANTED framework and used to create QSDB Database's collection of clickable networks. Each network is laid out according to SBGN standards, showing quorum sensing and quorum quenching interactions between organisms and signaling molecules. Thi... |
