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May 15, 2024 - C03: Modelling of material injection processes into porous structures applied to vertebroplasty
Trivedi, Zubin; Wychowaniec, Jacek K.; Gehweiler, Dominic; Sprecher, Christoph Martin; Boger, Andreas; Gueorguiev, Boyko; D'Este, Matteo; Ricken, Tim; Röhrle, Oliver, 2024, "Data for: Rheological Analysis and Evaluation of Measurement Techniques for the Curing Polymethylmethacrylate Bone Cement in Vertebroplasty", https://doi.org/10.18419/darus-4004, DaRUS, V1, UNF:6:qWipgRgsaAlTQZDkmPv0LQ== [fileUNF]
This dataset includes the measurement data described in the paper "Rheological Analysis and Evaluation of Measurement Techniques for the Curing Polymethylmethacrylate Bone Cement in Vertebroplasty" and additional supplementary data. All data in .csv files except 'Inj1 -- 5' are g...
Mar 28, 2024 - MD Simulations
Jeltsch, Albert; Schnee, Philipp; Pleiss, Jürgen; Weirich, Sara, 2024, "Additional data related to Weirich et al.: Discovery of new NSD2 non-histone substrates and design of a super-substrate", https://doi.org/10.18419/darus-3815, DaRUS, V1
This data collection contains additional data related to Weirich et al.: "Discovery of new NSD2 non-histone substrates and design of a super-substrate". This includes Modelled structures of NSD2 bound to different peptides Source data of the results of the MD analysis MD simulati...
Mar 19, 2024 - Institute for Stochastics and Applications
Höpfl, Sebastian, 2024, "Percentile Intervals in Bayesian Inference are Overconfident", https://doi.org/10.18419/darus-4068, DaRUS, V1
This dataset demonstrates the difference in calculating percentile Intervals as approximation for Highest Density Intervals (HDI) vs. Highest Posterior Density (HPD). This is demonstrated with extended partial liver resection data (ZeLeR-study, ethical vote: 2018-1246-Material)....
Mar 4, 2024 - Amplicon based bisulfite NGS data
Jeltsch, Albert; Bashtrykov, Pavel; Dossmann, Leonie; Emperle, Max, 2024, "NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons", https://doi.org/10.18419/darus-3386, DaRUS, V1
Cloning and site-directed mutagenesis The gene of the catalytic, C-terminal domain of murine DNMT3C (amino acid residues 439-740 of P0DOY1) was obtained in E. coli codon optimized form from IDT Integrated DNA Technologies. The gene fragment was cloned with the StrataClone PCR Clo...
Jan 10, 2024 - Amplicon based bisulfite NGS data
Jeltsch, Albert; Bashtrykov, Pavel; Albrecht, Claudia, 2024, "NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1", https://doi.org/10.18419/darus-3790, DaRUS, V1
Method overview For targeted DNA demethylation of the H19/IGF2 ICR1, HEK293 cells were transfected with two plasmids, one containing dCas9 fused to a SunTag with five repeats of the GCN4 peptide, separated by 22 aa long linkers, and scFv-fused TET1CD, as well as a GFP reporter pr...
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