1 to 7 of 7 Results
Jan 12, 2024 - Amplicon based bisulfite NGS data
Jeltsch, Albert; Bashtrykov, Pavel; Rajaram, Nivethika, 2023, "NGS data related to Rajaram et al.: Development of super-specific epigenome editing by targeted allele-specific DNA methylation", https://doi.org/10.18419/darus-3581, DaRUS, V2
Method overview To achieve targeted ASM, transient transfection of the dCas9-10X SunTag-BFP, scFv-DNMT3A-3L-sfGFP, and sgRNA-DsRed plasmids was performed in HEK293 cells. Control experiments were conducted with a scrambled sgRNA that does not have a binding site in the human geno... |
Dec 4, 2023 - Institute for Modelling and Simulation of Biomechanical Systems
Schmid, Laura; Klotz, Thomas; Röhrle, Oliver; Powers, Randall K.; Negro, Francesco; Yavuz, Utku S., 2023, "Replication Data for “Postinhibitory excitation in motoneurons can be facilitated by hyperpolarization-activated inward currents: a simulation study”", https://doi.org/10.18419/darus-3686, DaRUS, V1
This dataset contains spiketrains from experimental as well as simulated motoneurons that were analysed for the publication Postinhibitory excitation in motoneurons can be facilitated by hyperpolarization-activated inward currents: a simulation study. Abstract: Postinhibitory exc... |
Nov 20, 2023 - SPP2311: Ultrasound Neuromodulation
Werneck, Linda; Yildiz, Erdost; Han, Mertcan; Keip, Marc-Andre; Sitti, Metin; Ortiz, Michael, 2023, "Ion Flow Through Neural Ion Membrane: scripts and data", https://doi.org/10.18419/darus-3575, DaRUS, V1
The scripts and data are related to the numerical implementation of a quantitative model for ion flow through neural ion channels and a validation of the underlying single ion channel flow model for gramicidin A channels. The model is based on the Poisson-Nernst-Planck (PNP) equa... |
Jul 21, 2023 - HLRS-NUM-Biomechanics
Gebert, Johannes; Schneider, Ralf; Schnabel, Benjamin; Pelzer, Fabian; Helwig, Peter; Schenkengel, Jan-Peter, 2023, "Scanning Spongiosa: A set of Clinical Computed Tomography Scans of Human Femoral Heads", https://doi.org/10.18419/darus-3065, DaRUS, V1
Clinical computed tomography scans of 28 human femoral heads. They were explanted during total hip arthroplasty. |
Jun 21, 2023 - Neck Reflex Behavior in Driving Simulator Experiments
Kempter, Fabian; Lantella, Lorena; Stutzig, Norman; Fehr, Jörg; Siebert, Tobias, 2023, "Neck Reflex Behavior in Driving Simulator Experiments - Academic-Scale Simulator at ITM", https://doi.org/10.18419/darus-3000, DaRUS, V1
Neck movement and injury during a car crash is influenced by reflexes, strength, and flexibility. This data set contains in-vivo measurements of neck kinematics and reflexes as participants are rapidly accelerated while driving a mechanically simulated car. This data set includes... |
Jeltsch, Albert; Bashtrykov, Pavel; Adam, Sabrina, 2023, "NGS data related to Adam et al.: On the accuracy of the epigenetic copy machine - comprehensive specificity analysis of the DNMT1 DNA methyltransferase", https://doi.org/10.18419/darus-3334, DaRUS, V2, UNF:6:ERMvcNuV8nq+mI9Q5Xu53A== [fileUNF]
Expression and purification of DNMT1 for biochemical work Full length murine DNMT1 (UniProtKB P13864) was overexpressed and purified as described (Adam, et al. 2020) using the Bac-to-Bac baculovirus expression system (Invitrogen). The expression construct of the DNMT1 with mutate... |
Jeltsch, Albert; Schnee, Philipp; Saad, Mina; Weirich, Sara; Pleiss, Jürgen; Bashtrykov, Pavel, 2023, "Additional data related to Khella et al.: The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation", https://doi.org/10.18419/darus-3263, DaRUS, V1
This data collection contains additional data related to Khella et al.: "The T1150A cancer mutant of the protein lysine methyltransferase NSD2 can introduce H3K36 trimethylation". This includes Movie 1: Example of a successful docking of AdoMet to the NSD2 T1150A - H3K36me2 pepti... |
