1 to 10 of 18 Results
Höpfl, Sebastian, 2024, "Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a", https://doi.org/10.18419/darus-3838, DaRUS, V1, UNF:6:az4wbAbWWcIbbLxQh/QPXA== [fileUNF]
This dataset contains the proposed sphingolipid rheostat model with mass-action kinetics and a proposed negative feedback from ceramide to its synthesis from Sphinganine. The model is written in the Systems Biology Markup Language (SBML) and with the experimental data, experiment... |
Mar 28, 2024 - MD Simulations
Jeltsch, Albert; Schnee, Philipp; Pleiss, Jürgen; Weirich, Sara, 2024, "Additional data related to Weirich et al.: Discovery of new NSD2 non-histone substrates and design of a super-substrate", https://doi.org/10.18419/darus-3815, DaRUS, V1
This data collection contains additional data related to Weirich et al.: "Discovery of new NSD2 non-histone substrates and design of a super-substrate". This includes Modelled structures of NSD2 bound to different peptides Source data of the results of the MD analysis MD simulati... |
Jeltsch, Albert; Bashtrykov, Pavel; Dossmann, Leonie; Emperle, Max, 2024, "NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons", https://doi.org/10.18419/darus-3386, DaRUS, V1
Cloning and site-directed mutagenesis The gene of the catalytic, C-terminal domain of murine DNMT3C (amino acid residues 439-740 of P0DOY1) was obtained in E. coli codon optimized form from IDT Integrated DNA Technologies. The gene fragment was cloned with the StrataClone PCR Clo... |
Mikheev, Vladimir; Skukies, Rene; Ehinger, Benedikt, 2023, "Supplementary material: "The Art of Brainwaves: A Survey on Event-Related Potential Visualization Practices"", https://doi.org/10.18419/darus-3729, DaRUS, V2, UNF:6:+qePfVjlqif+DUSlAZSsrw== [fileUNF]
The purpose related to this dataset is to investigate the state of visualization in ERP (Event-Related Potential) research. The investigation was conducted through an online questionnaire administered via LimeSurvey Community Edition v5.4.7, hosted by the University of Stuttgart.... |
Jan 16, 2024 - Institute for Modelling and Simulation of Biomechanical Systems
Nadler, Tobias; Wolfen, Simon; Häufle, Daniel F. B.; Schmitt, Syn, 2024, "Technical specifications and details of the muscle-driven biorobotic arm ATARO", https://doi.org/10.18419/darus-3813, DaRUS, V1
ATARO is a bio-inspired arm robot with two degrees of freedom. Five artificial muscle-spring units (MSUs) are used for actuation. The MSUs, each consisting of a pneumatic artificial muscle (PAM) and a spring in series, mimic the characteristics of the human muscle-tendon complex.... |
Jan 12, 2024 - Amplicon based bisulfite NGS data
Jeltsch, Albert; Bashtrykov, Pavel; Rajaram, Nivethika, 2023, "NGS data related to Rajaram et al.: Development of super-specific epigenome editing by targeted allele-specific DNA methylation", https://doi.org/10.18419/darus-3581, DaRUS, V2
Method overview To achieve targeted ASM, transient transfection of the dCas9-10X SunTag-BFP, scFv-DNMT3A-3L-sfGFP, and sgRNA-DsRed plasmids was performed in HEK293 cells. Control experiments were conducted with a scrambled sgRNA that does not have a binding site in the human geno... |
Jan 10, 2024 - Amplicon based bisulfite NGS data
Jeltsch, Albert; Bashtrykov, Pavel; Albrecht, Claudia, 2024, "NGS data related to Albrecht et al.: Locus specific and stable DNA demethylation at the H19/IGF2 ICR1 by epigenome editing using a dCas9-SunTag system and the catalytic domain of TET1", https://doi.org/10.18419/darus-3790, DaRUS, V1
Method overview For targeted DNA demethylation of the H19/IGF2 ICR1, HEK293 cells were transfected with two plasmids, one containing dCas9 fused to a SunTag with five repeats of the GCN4 peptide, separated by 22 aa long linkers, and scFv-fused TET1CD, as well as a GFP reporter pr... |
Dec 15, 2023 - PN 2-3B
Santana Chacon, Pablo Filipe; Hammer, Maria; Wochner, Isabell; Walter, Johannes R.; Schmitt, Syn, 2023, "Replication Data for: A physiologically enhanced muscle spindle model: using a Hill-type model for extrafusal fibers as template for intrafusal fibers", https://doi.org/10.18419/darus-3796, DaRUS, V1
This code/data allows you reproduce the results of the paper: "A physiologically enhanced muscle spindle model: using a Hill-type model for extrafusal fibers as template for intrafusal fibers" by P. F. S. Chacon, M. Hammer, I. Wochner, J. R. Walter and S. Schmitt. Always cite the... |
Dec 4, 2023 - Institute for Modelling and Simulation of Biomechanical Systems
Schmid, Laura; Klotz, Thomas; Röhrle, Oliver; Powers, Randall K.; Negro, Francesco; Yavuz, Utku S., 2023, "Replication Data for “Postinhibitory excitation in motoneurons can be facilitated by hyperpolarization-activated inward currents: a simulation study”", https://doi.org/10.18419/darus-3686, DaRUS, V1
This dataset contains spiketrains from experimental as well as simulated motoneurons that were analysed for the publication Postinhibitory excitation in motoneurons can be facilitated by hyperpolarization-activated inward currents: a simulation study. Abstract: Postinhibitory exc... |
Nov 28, 2023 - Neutral Body Posture
Lerge, Patrick; Nölle, Lennart Vincent; Schmitt, Syn, 2023, "Replication Data for: "Deep learning-based estimation of the neutral body posture considering three-dimensional local joint angles"", https://doi.org/10.18419/darus-3793, DaRUS, V1
This dataset contains the pose estimation results from the third-party framework "PARE" (Max Planck Institute for Intelligent Systems) and the pose averaging script (Matlab, Mathworks, Natick, MA) to obtain the joint angle results described in the paper "Deep learning-based estim... |
