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Subject: Medicine, Health and Life Sciences

1 to 10 of 151 Results

Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a Apr 11, 2024 - Institute for Stochastics and Applications Höpfl, Sebastian, 2024, "Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a", https://doi.org/10.18419/darus-3838, DaRUS, V1, UNF:6:az4wbAbWWcIbbLxQh/QPXA== [fileUNF] This dataset contains the proposed sphingolipid rheostat model with mass-action kinetics and a proposed negative feedback from ceramide to its synthesis from Sphinganine. The model is written in the Systems Biology Markup Language (SBML) and with the experimental data, experiment...
COLife_04 - Multi-Scale More-than-Human Atlas Gigamaping, Ecosystem Mapping and CoDesigning Apr 10, 2024 - EXC IntCDC Research Project 29 'COLife: More-Than-Human Perspective to Codesign' Davidova, Marie; Porqueddu, Elena; Behnam, Hananeh; Valverde Rojas, María Claudia; Zímová, Kateřina; Gazdová, Kateřina; Sweeting, Ben; Goodbun, John; Perera, Dulmini; Sadler, Simon; Huthöfer, Stefanie, 2024, "COLife_04 - Multi-Scale More-than-Human Atlas Gigamaping, Ecosystem Mapping and CoDesigning", https://doi.org/10.18419/darus-4123, DaRUS, V1, UNF:6:rYSRFONRqVBOzoG7Tj9Imw== [fileUNF] The dataset presents the Multi-Scale More-than-Human Atlas Gigamapping Workshop output that should evaluate and suggest new developments of COLife project prototyping. We also gathered the ecological check data and planted new species with gardening and seedbombs. This was all el...
MRI based perfusion of rats with 60% PVL Apr 9, 2024 - Mathematical modeling and simulation of cellular systems Herrmann, Karl-Heinz; Zhao, Wan-Ting; Höpfl, Sebastian; Reichenbach, Jürgen R., 2024, "MRI based perfusion of rats with 60% PVL", https://doi.org/10.18419/darus-3878, DaRUS, V1, UNF:6:sQocf/P7vdAmWMQR6rEEJw== [fileUNF] The study investigates in vivo liver perfusion in rats. Perfusion of ligated and non-ligated liver lobes of 25 rats was monitored via MRI. Rats were subjected to 60% Portal Vein Ligation (PVL). Experimentally, the left stem of the portal vein (supplying Left Median (LML) and Left...
Bayesian Modeling of Time Series Data (BayModTS) Apr 8, 2024 - Mathematical modeling and simulation of cellular systems Höpfl, Sebastian, 2024, "Bayesian Modeling of Time Series Data (BayModTS)", https://doi.org/10.18419/darus-3876, DaRUS, V1 BayModTS is a FAIR workflow for processing highly variable and sparse data. The code and results of the examples in the BayModTS paper are stored in this repository. A maintained version of BayModTS that can be applied to your personal applications can be found on Git Hub.
Mathematical modeling and simulation of cellular systems(Universität Stuttgart) Apr 4, 2024Institute for Stochastics and Applications
COLridor - Responsive Wood Insect Hotels Apr 3, 2024 - EXC IntCDC Research Project 29 'COLife: More-Than-Human Perspective to Codesign' Davidova, Marie; Prokop, Šimon; Zímová, Kateřina; Goryczka, Kateřina; Michálek, Ondřej; Psaras, Michalis; Konatzii, Panagiota; Kyprianou, Stefanos; Vučić, Marko; Hanzlík, Krištof; Trgala, Kamil; Oberhofnerová, Eliška, 2024, "COLridor - Responsive Wood Insect Hotels", https://doi.org/10.18419/darus-4117, DaRUS, V1, UNF:6:riO2bjLr1WMBhu0Y14DeAA== [fileUNF] The dataset is releasing fabrication data of two prototypes produced in Prague - TreeHugger CZ and Nicosia - TreeHugger CY. These are responsive wood insect hotels produced in 2017 and 18, respectively. The data were adapted for Rhino 8. TreeHugger CY also involves instructions....
HPLC raw data related to Koeppl et al.: Structure, function and substrate preferences of archaeal S-adenosyl-L-homocysteine hydrolases Mar 28, 2024 - Institute of Biochemistry and Technical Biochemistry Koeppl, Lars-Hendrik, 2024, "HPLC raw data related to Koeppl et al.: Structure, function and substrate preferences of archaeal S-adenosyl-L-homocysteine hydrolases", https://doi.org/10.18419/darus-4052, DaRUS, V1, UNF:6:WOWb9VZ7dRJmQmW8TZ5lMg== [fileUNF] In this study, synthesis and cleavage reactions catalysed by S-adenosyl-L-homocysteine hydrolases originating from different domains of life were investigated. The reactions were studied using S-adenosyl-L-homocysteine or S-inosyl-L-homocysteine as substrate for the cleavage reac...
Additional data related to Weirich et al.: Discovery of new NSD2 non-histone substrates and design of a super-substrate Mar 28, 2024 - MD Simulations Jeltsch, Albert; Schnee, Philipp; Pleiss, Jürgen; Weirich, Sara, 2024, "Additional data related to Weirich et al.: Discovery of new NSD2 non-histone substrates and design of a super-substrate", https://doi.org/10.18419/darus-3815, DaRUS, V1 This data collection contains additional data related to Weirich et al.: "Discovery of new NSD2 non-histone substrates and design of a super-substrate". This includes Modelled structures of NSD2 bound to different peptides Source data of the results of the MD analysis MD simulati...
Percentile Intervals in Bayesian Inference are Overconfident Mar 19, 2024 - Institute for Stochastics and Applications Höpfl, Sebastian, 2024, "Percentile Intervals in Bayesian Inference are Overconfident", https://doi.org/10.18419/darus-4068, DaRUS, V1 This dataset demonstrates the difference in calculating percentile Intervals as approximation for Highest Density Intervals (HDI) vs. Highest Posterior Density (HPD). This is demonstrated with extended partial liver resection data (ZeLeR-study, ethical vote: 2018-1246-Material)....
NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons Mar 4, 2024 - Amplicon based bisulfite NGS data Jeltsch, Albert; Bashtrykov, Pavel; Dossmann, Leonie; Emperle, Max, 2024, "NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons", https://doi.org/10.18419/darus-3386, DaRUS, V1 Cloning and site-directed mutagenesis The gene of the catalytic, C-terminal domain of murine DNMT3C (amino acid residues 439-740 of P0DOY1) was obtained in E. coli codon optimized form from IDT Integrated DNA Technologies. The gene fragment was cloned with the StrataClone PCR Clo...

Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a

Apr 11, 2024 - Institute for Stochastics and Applications

Höpfl, Sebastian, 2024, "Modeling the sphingolipid rheostat under wild-type and hypomorph Hai1a", https://doi.org/10.18419/darus-3838, DaRUS, V1, UNF:6:az4wbAbWWcIbbLxQh/QPXA== [fileUNF]

This dataset contains the proposed sphingolipid rheostat model with mass-action kinetics and a proposed negative feedback from ceramide to its synthesis from Sphinganine. The model is written in the Systems Biology Markup Language (SBML) and with the experimental data, experiment...

COLife_04 - Multi-Scale More-than-Human Atlas Gigamaping, Ecosystem Mapping and CoDesigning

Apr 10, 2024 - EXC IntCDC Research Project 29 'COLife: More-Than-Human Perspective to Codesign'

Davidova, Marie; Porqueddu, Elena; Behnam, Hananeh; Valverde Rojas, María Claudia; Zímová, Kateřina; Gazdová, Kateřina; Sweeting, Ben; Goodbun, John; Perera, Dulmini; Sadler, Simon; Huthöfer, Stefanie, 2024, "COLife_04 - Multi-Scale More-than-Human Atlas Gigamaping, Ecosystem Mapping and CoDesigning", https://doi.org/10.18419/darus-4123, DaRUS, V1, UNF:6:rYSRFONRqVBOzoG7Tj9Imw== [fileUNF]

The dataset presents the Multi-Scale More-than-Human Atlas Gigamapping Workshop output that should evaluate and suggest new developments of COLife project prototyping. We also gathered the ecological check data and planted new species with gardening and seedbombs. This was all el...

MRI based perfusion of rats with 60% PVL

Apr 9, 2024 - Mathematical modeling and simulation of cellular systems

Herrmann, Karl-Heinz; Zhao, Wan-Ting; Höpfl, Sebastian; Reichenbach, Jürgen R., 2024, "MRI based perfusion of rats with 60% PVL", https://doi.org/10.18419/darus-3878, DaRUS, V1, UNF:6:sQocf/P7vdAmWMQR6rEEJw== [fileUNF]

The study investigates in vivo liver perfusion in rats. Perfusion of ligated and non-ligated liver lobes of 25 rats was monitored via MRI. Rats were subjected to 60% Portal Vein Ligation (PVL). Experimentally, the left stem of the portal vein (supplying Left Median (LML) and Left...

Bayesian Modeling of Time Series Data (BayModTS)

Apr 8, 2024 - Mathematical modeling and simulation of cellular systems

Höpfl, Sebastian, 2024, "Bayesian Modeling of Time Series Data (BayModTS)", https://doi.org/10.18419/darus-3876, DaRUS, V1

BayModTS is a FAIR workflow for processing highly variable and sparse data. The code and results of the examples in the BayModTS paper are stored in this repository. A maintained version of BayModTS that can be applied to your personal applications can be found on Git Hub.

Mathematical modeling and simulation of cellular systems(Universität Stuttgart)

Apr 4, 2024Institute for Stochastics and Applications

COLridor - Responsive Wood Insect Hotels

Apr 3, 2024 - EXC IntCDC Research Project 29 'COLife: More-Than-Human Perspective to Codesign'

Davidova, Marie; Prokop, Šimon; Zímová, Kateřina; Goryczka, Kateřina; Michálek, Ondřej; Psaras, Michalis; Konatzii, Panagiota; Kyprianou, Stefanos; Vučić, Marko; Hanzlík, Krištof; Trgala, Kamil; Oberhofnerová, Eliška, 2024, "COLridor - Responsive Wood Insect Hotels", https://doi.org/10.18419/darus-4117, DaRUS, V1, UNF:6:riO2bjLr1WMBhu0Y14DeAA== [fileUNF]

The dataset is releasing fabrication data of two prototypes produced in Prague - TreeHugger CZ and Nicosia - TreeHugger CY. These are responsive wood insect hotels produced in 2017 and 18, respectively. The data were adapted for Rhino 8. TreeHugger CY also involves instructions....

HPLC raw data related to Koeppl et al.: Structure, function and substrate preferences of archaeal S-adenosyl-L-homocysteine hydrolases

Mar 28, 2024 - Institute of Biochemistry and Technical Biochemistry

Koeppl, Lars-Hendrik, 2024, "HPLC raw data related to Koeppl et al.: Structure, function and substrate preferences of archaeal S-adenosyl-L-homocysteine hydrolases", https://doi.org/10.18419/darus-4052, DaRUS, V1, UNF:6:WOWb9VZ7dRJmQmW8TZ5lMg== [fileUNF]

In this study, synthesis and cleavage reactions catalysed by S-adenosyl-L-homocysteine hydrolases originating from different domains of life were investigated. The reactions were studied using S-adenosyl-L-homocysteine or S-inosyl-L-homocysteine as substrate for the cleavage reac...

Additional data related to Weirich et al.: Discovery of new NSD2 non-histone substrates and design of a super-substrate

Mar 28, 2024 - MD Simulations

Jeltsch, Albert; Schnee, Philipp; Pleiss, Jürgen; Weirich, Sara, 2024, "Additional data related to Weirich et al.: Discovery of new NSD2 non-histone substrates and design of a super-substrate", https://doi.org/10.18419/darus-3815, DaRUS, V1

This data collection contains additional data related to Weirich et al.: "Discovery of new NSD2 non-histone substrates and design of a super-substrate". This includes Modelled structures of NSD2 bound to different peptides Source data of the results of the MD analysis MD simulati...

Percentile Intervals in Bayesian Inference are Overconfident

Mar 19, 2024 - Institute for Stochastics and Applications

Höpfl, Sebastian, 2024, "Percentile Intervals in Bayesian Inference are Overconfident", https://doi.org/10.18419/darus-4068, DaRUS, V1

This dataset demonstrates the difference in calculating percentile Intervals as approximation for Highest Density Intervals (HDI) vs. Highest Posterior Density (HPD). This is demonstrated with extended partial liver resection data (ZeLeR-study, ethical vote: 2018-1246-Material)....

NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons

Mar 4, 2024 - Amplicon based bisulfite NGS data

Jeltsch, Albert; Bashtrykov, Pavel; Dossmann, Leonie; Emperle, Max, 2024, "NGS data related to Dossmann et al.: Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons", https://doi.org/10.18419/darus-3386, DaRUS, V1

Cloning and site-directed mutagenesis The gene of the catalytic, C-terminal domain of murine DNMT3C (amino acid residues 439-740 of P0DOY1) was obtained in E. coli codon optimized form from IDT Integrated DNA Technologies. The gene fragment was cloned with the StrataClone PCR Clo...

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